Research Fellow Full-time NEW

Research Fellow

Applications are invited to fill a Post-doctoral Research Fellow position in an exciting research programme based at the UCL Great Ormond Street Institute of Child Health and the UCL EGA Institute for Women's Health. The aim of this research is to develop a novel gene therapy treatment to ameliorate the disease phenotype of a well characterised transgenic mouse model of mitochondrial disease. The successful candidate will contribute to the following aspects of the research programme: AAV vector production, in vivo testing of AAV gene therapy treatment for a well-characterised transgenic mouse model of mitochondrial disease, evaluation of efficacy of viral gene therapy in rescuing mitochondrial dysfunction through behavioural and tissue analyses including qPCR, Western blot and immunohistochemistry on mouse tissues, establishing new disease outcome measures. This post is funded for 2 years full time.

Applicants must have a higher degree in a relevant discipline (Neuroscience or genetics or gene therapy or another relevant subject area) at PhD level. Previous experience with mouse in vivo research is essential. A Home Office animal licence is essential. Experience in viral vector production and mouse in vivo gene therapy methodologies are strongly desirable. Molecular biology, cell biology, western blot and immunohistochemical experience is essential.

As well as the exciting opportunities this role presents, we also offer some great benefits some of which are below: 41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days), additional 5 days' annual leave purchase scheme, defined benefit career average revalued earnings pension scheme (CARE), cycle to work scheme and season ticket loan, immigration loan, relocation scheme for certain posts, on-site nursery, on-site gym, enhanced maternity, paternity and adoption pay, employee assistance programme: Staff Support Service, discounted medical insurance. Visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out more.

As London's Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world's talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL's workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. You can read more about our commitment to Equality, Diversity and Inclusion here: https://www.ucl.ac.uk/equality-diversity-inclusion/ If you have any queries regarding the application process, please contact Madhur Sharma on ich.hr@ucl.ac.uk quoting job reference.