Research Fellow (Cell Biology/Biophysics/Bioengineering/Biochemistry) Full-time

Postdoc Research Fellow

We are looking for a highly motivated and creative Postdoc Research Fellow to join our team and lead an exciting project investigating the functional interactions between biomolecular condensates and membrane-bound organelles in different cellular models. This project aims to bridge the gap between membrane-less and membrane-bound compartments, deciphering how phase separation influences organelle dynamics, signaling, and function.

Key Responsibilities:

1. Research Leadership: Spearhead an independent project decoding the functional crosstalk between condensates and membrane-bound organelles.
2. Tool Engineering: Design and validate novel molecular probes or synthetic condensates, leveraging genetic engineering or generative protein design.
3. Quantitative Imaging: Apply advanced microscopy and image analysis pipelines to measure biophysical dynamics in living cells.
4. Output & Mentorship: Drive the publication of high-impact findings and assist in the supervision of junior lab members.

Requirements:

• PhD in Cell Biology, Biophysics, Bioengineering, Biochemistry, or a related field

• Core Expertise: Strong background in the biophysics of biomolecular condensates (phase separation) and fundamental cell biology.

• Genetic Engineering: Advanced cloning techniques, CRISPR/Cas9 editing, or optogenetic tool development.

• Quantitative Imaging: Live-cell confocal and/or super-resolution microscopy, or automated image analysis pipelines.

• Computational Protein Design: Experience with generative models (e.g., AlphaFold, RFdiffusion, ProteinMPNN) for designing novel condensate drivers or sensors.

• Collaborative and interdisciplinary research environment.

• Access to state-of-the-art imaging and biophysical instrumentation.

• Mentorship committed to your career development and independence.

We regret to inform that only shortlisted candidates will be notified.

Hiring Institution: NTU