Research Senior Scientist, Lead Profiling Full-time

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

Takeda's Lead Profiling team is building a new team of experienced, innovative, and collaborative researchers to partner with the Gastrointestinal and Inflammation (GI2) Drug Discovery Unit to design and run high throughput automated assays on state-of-the-art robotic platforms to drive an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, and inflammatory diseases with high unmet medical needs. We seek a skilled Research Sr. Scientist to join our Lead Profiling and cross-functional discovery teams.

Design and execute pre-clinical pharmacology strategies on fully automated robotic platforms to support candidate selection, accelerating clinical translation of impactful therapies for patients with inflammatory and autoimmune disorders.

Provide deep scientific expertise in the design and execution of miniaturized, high throughput assays for immunology/cellular pharmacology, acting as a subject matter expert across cross-functional teams.

Leverage state-of-the-art automation to streamline complex biology screening workflows and manage data across GI2 programs, in close collaboration with Takeda scientists and external partners.

Develop and implement fully-automated screening workflows to support multiple programs in the GI2 portfolio.

Champion scientific integrity and rigor in data analysis, preparation, and interpretation of detailed protocols/SOPs.

Collaborate effectively within a matrixed structure, clearly communicate results, challenges, and impact through presentations and discussions with broad audiences. Integrate data from cross-functional teams to drive decision-making.

Think independently and creatively to explore novel drug discovery approaches to create therapies for patients suffering from immune driven disorders.

Expected: PhD degree in immunology/pharmacology with 2+ years industry experience, or MS with 8+ years' experience, or BS with 10+ years of relevant experience in pharmaceutical/biotech R&D.

Strong expertise and depth of knowledge in complex cell-based assay development and screening technologies (e.g., Flow cytometry, AlphaLISA, TR-FRET, ELISA and etc).

Extensive experience with state-of-the-art automation and assay miniaturization to streamline assay workflows.

Significant experience leveraging high throughput data analysis platforms and LIMS systems for automated data analysis, QC and reporting

Foundational knowledge in engineering and programming is highly desirable

Proven experience in developing and/or evaluating novel small molecule and biologics

Stays current with emerging scientific literature, competitive landscapes, and innovative technologies

The position will be based in Cambridge, MA. This position is currently classified as “hybrid” by Takeda's Hybrid and Remote Work policy.

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location: Boston, MA

U.S. Base Salary Range: $137,000.00 – $215,270.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.