A Research Technician position is available to investigate how pre-existing antibodies shape subsequent immune responses through antibody feedback, funded by the Wellcome Trust. This project addresses a fundamental question in immunology: how do pre-existing antibodies shape subsequent immune responses to influenza, SARS-CoV-2 and Japanese Encephalitis vaccination? This will be assessed through serum immunodominance profiling, FACS-based single B cell cloning and functional antibody characterisation alongside high-throughput B cell receptor (BCR) sequencing. The project brings together experimental and computational approaches across multiple international sites to define the rules governing antibody feedback in human immunity. Therefore, the successful candidate will work closely with the PI and the interdisciplinary team of co-PIs outside of UCL study antibody feedback across computational and in vitro modelling of germinal centre responses. This is a fixed term position available for 1 year from July 2026.
The postholder will provide technical research support essential to the functioning of the McCoy lab. Their overall supervision will be directed by Dr McCoy. They will assist/perform cutting-edge laboratory-based research interlinking components of the project. The successful candidate will perform binding and functional serology across multiple cohorts. Suitability will be assessed by the written application and then by a short-written test and an interview. Please see the attached job description and person specification for full details. Please also read the attached Candidate Guidance document. If you have any queries about the role or application process, technical issues, or need reasonable adjustments or a more accessible format to apply for this job online, please contact the staffing team at hr.ii@ucl.ac.uk.
As well as the exciting opportunities this role presents, we also offer some great benefits some of which are below:
Visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out more.
As London's Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world's talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL's workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. Our department holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality.
Tagged as: Life Sciences
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