Scientist 3 – Translational Medicine (Ophthalmology) Full-time

Scientist 3 – Translational Medicine (Ophthalmology)

Genentech's Translational Medicine OMNI (TM OMNI) Department supports the entire R&D portfolio of novel therapies in Ophthalmology, Metabolism, Neuroscience, Immunology, and Infectious Diseases (OMNI). We develop and implement biomarker strategies to study disease pathways, confirm a therapeutic's mechanism of action, and improve clinical trial efficiency and success. Additionally, we lead reverse translation efforts, leveraging clinical data to support target discovery.

We are seeking a talented and highly motivated Scientist 3/4 to join Genentech's Translational Medicine (TM) team on-site at our South San Francisco campus. The candidate will collaborate with scientists across R&D to provide biomarker support for ophthalmology programs across different stages of drug development while also generating insights for the next generation of ophthalmology drug targets. The role will cover: 1) Analysis and interpretation of large-scale -omics datasets from clinical and preclinical studies to enable biomarker discovery and reverse translation; 2) Assay development to support biomarker assessment in clinical and preclinical studies.

Responsibilities

• Analyze large scale -omics datasets (proteomics, lipidomics, transcriptomics) generated from clinical and preclinical sample testing.
• Discover candidate targets based on interpretation of -omics data and a deep understanding of disease biology.
• Develop, qualify, and validate custom immunoassays (e.g., ELISA, Simoa, NULISA) against biomarkers of interest to support pipeline programs (goes beyond running commercial assay kits).
• Clearly and concisely communicate findings internally and externally through written reports, publications, and presentations.
• Coordinate interdepartmental and external collaborations.

Who You Are

• A PhD in Biological Sciences with a strong record of high-impact publications with both bioinformatics and wet lab experience. Industry experience preferred.
• Excellent teamwork, communication, time management, organization skills, and ability to work independently.
• Excellent oral and written presentation skills, creative problem-solving abilities, and a passion for drug discovery and development.

The expected salary range for this position based on the primary location of California is $100,400.00 – $186,400.00 Annually. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

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