Scientist/Associate Scientist: 3D Engineered In Vitro Models Full-time

Bench Scientist

We are seeking a motivated, creative, and meticulous bench scientist with a track record in developing 3D Cell and Tissue Models. The candidate will join the Translational Models group within our Human Biology department in GSK's Research Technologies organization at the Upper Providence site in the United States. The translational model teams' mission is to improve predictive and translational value of preclinical 3D cell and tissue models for identification of new targets, mechanism of action, efficacy, safety, and metabolism. We aim to ultimately use these systems to refine, reduce, and replace animal models. Our group engages in dynamic, matrixed collaborative projects across therapeutic areas working closely with research units and technology platform groups.

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. By uniting science, technology, and talent, we are committed to getting ahead of disease together.

Responsibilities include:

• Perform assays to characterize cells, organoids, micro physiological systems and 3D bio printed constructs.
• Fabricate and test microfluidic devices for cell and tissue phenotypes.
• Maintain inventory of cells, reagents and assays to support a matrix team in a cross-functional environment to ensure optimal delivery of project and department objectives to the highest possible scientific standard.
• Support protocol development, maintenance of laboratory equipment and conduct routine experiments to advance therapeutic pipeline.

Basic Qualifications

• Bachelor's in biomedical engineering, Bioengineering, Chemical Engineering, Biomedical Sciences or related discipline.
• 1+ years' experience in primary cells, induced pluripotent stem cells and tissue-derived stem cells.
• Experience with biological assays including imaging-based analysis.

Preferred Experience

• Masters degree.
• 3+ years of experience in microfabrication and microfluidics based in vitro models.
• Experience in supporting research and development of multicellular 3D in vitro models.
• Significant laboratory work with histopathology, flow cytometry/FACS, ELISA/Luminex/MSD, qPCR and confocal microscopy.
• Prior knowledge on integration of automation technologies with microfabricated systems.
• Experience with CAD, MS office, complex data analysis and statistical software.
• Excellent written and oral communication skills.