Scientist – Biomolecular Interactions Full-time NEW

Scientist, Biomolecular Interactions Group

Join AstraZeneca's Biologics Engineering (BE) team, where we turn ideas into life-changing medicines. We are looking for a motivated scientist to join our Biomolecular Interactions Group (BMIG) within the multidisciplinary Protein Analytics & Developability team. As a Scientist in the Biomolecular Interactions Group, you will be instrumental in advancing our kinetic characterization of antibody-antigen and antibody Fc receptor interactions in late discovery, early development, and pre-clinical stages. Reporting to the Associate Director of the Biomolecular Interactions group, the successful candidate will work closely with a multidisciplinary team in a lab-based role to support the later stages of our pipeline projects and contribute to the enhancement of our technology platforms.

Key Accountabilities:

• Independently design, perform, and interpret SPR-based kinetic assays across various formats, including mono- and multi-specific molecules, ADCs, and radioconjugates.
• Conduct detailed studies of Fc receptor interactions by SPR and chromatographic techniques.
• Analyze complex biosensor and chromatographic datasets; prepare detailed technical reports, and presentations.
• Present findings in collaborative scientific forums, contribute to project documentation, and drive scientific publications and patent applications.
• Stay current on advances in biosensor technologies, Fc biology, and novel approaches relevant to therapeutic molecule profiling.
• Engage with cross-functional colleagues across discovery, development, and clinical to share scientific insight and technical expertise to advance collective goals.

Essential Skills/Experience:

• Bachelor's with 5+ years of experience; Master's, preferably with 2+ years of experience in Biophysics, Biochemistry, Molecular Biology, or a closely related discipline.
• Demonstrated, hands-on experience in conducting biomolecular interaction assays using Surface Plasmon Resonance (SPR) is strongly preferred.
• Hands-on experience with chromatography equipment and methods (HPLC, FPLC, affinity chromatography, etc.) is strongly preferred.
• Experience in independently designing, troubleshooting, and optimizing experimental assays.
• Proficiency in data analysis and statistical methods.
• Experience communicating experimental results with clarity, both verbally and in writing, for a variety of scientific and regulatory audiences.
• Evidence of collaborative skills and ability to work effectively within multidisciplinary teams.

At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We're on an exciting journey to pioneer the future of healthcare.

Are you already imagining yourself joining our team? Good, because we can't wait to hear from you!