Scientist, Cell Therapy Development Full-time

Scientist, Cell Therapy Development

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

We are searching for the best talent for the Scientist, Cell Therapy Development to be in Spring House, PA.

Purpose

The Scientist will be a lab-based role, responsible for experimental studies in process development of CART cell therapies for early, mid, and late-stage new molecular entity (NMEs). This includes development and optimization of the technical operations associated with aseptic technique, cell culture, formulation and fill/finish, cryopreservation, diluent compatibility/administration relevant studies, as well as execution of characterization plans and stability campaigns.

You Will Be Responsible For:

• Development and optimization of cell therapy product
• Execution of characterization plans and stability studies with the goal of developing a better understanding of stabilization mechanisms.
• Perform technical analysis of the project data, including trending of data.
• Author technical reports and regulatory filling. Present data to peers and functional management.
• Design and execute studies relating to formulation and filling unit operations including mixing, vial, bag, and syringe filling, cryopreservation, and overseeing the execution of development, small scale to GMP grade fill/finish manufacturing processes.
• Design and manage stability studies on target and experimental formulations.
• Perform duties consistent with good laboratory practices.

Qualifications

Required:

• A B.S. or M.S. in a relevant scientific discipline with 1-2 years of related laboratory experience.
• Experience with mammalian cell culture.
• Ability to interpret and analyze data from biophysical assays and design appropriate experiments.
• Must have excellent strong written and verbal communication skills.

Preferred:

• Experience in CAR-T production/culture.
• Experience with mammalian cell cryopreservation/cryobiology.
• Experience implementing and maintaining high quality standards for all aspects of work conducted including adherence to regulatory GLP/GMP, departmental, and safety guidelines.
• Experience mentoring others in a matrix environment.
• This role may require up to 10% travel.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.