Scientist, Downstream Process Development Full-time

Scientist

For over 130 years, we have pioneered groundbreaking science. Today, we are driven by continuous innovation to develop breakthrough medicines, vaccines and technology. Rooted in direct experience on the farm and in the clinic, we work hand in hand with our customers every step of the way.

Our singular focus is to empower those who care for animals, helping them manage their vital responsibility with confidence. Because when it comes to animal health, no one sees it like we do.

We are seeking a highly motivated and skilled Scientist to join our Monoclonal Antibody Research team. The successful candidate will play a crucial role in the downstream processes development for the production of therapeutic monoclonal antibodies. This position requires a strong background in recombinant protein production and purification as well as knowledge of protein quality assessment. The candidate will be responsible for conducting the laboratory studies for the development of new or improved veterinary monoclonal antibody products.

Key Responsibilities:

• Participate in design and execution of research geared toward developing downstream processes for the purification of therapeutic proteins and monoclonal antibodies.
• Perform recombinant protein production and purification using various chromatography techniques (e.g., affinity, ion exchange, size exclusion).
• Perform standard laboratory work and routine maintenance of laboratory equipment
• Document experimental procedures, results, and conclusions in laboratory notebooks and technical reports
• Present findings and updates to project teams and stakeholders.
• Collaborate with other team members for quality assessment of purified proteins and support the downstream needs of other team members.
• Collaborate with cross-functional teams outside of the group

Qualifications

Education:

Bachelor's or Master's degree in Biochemistry, Biotechnology, Chemical Engineering, or a related field.

Required Experience and Skills:

• 5+ years of experience in recombinant protein purification.
• Hands-on experience with chromatography techniques and other protein purification methods.
• Proficiency in using laboratory software and data analysis tools related to downstream unit operation.
• Strong analytical and problem-solving skills.
• Excellent communication and teamwork abilities.
• Ability to work independently and manage multiple projects simultaneously.

Required Skills:

Accountability, Adaptability, Antibodies, Antibody Therapeutics, Assay Development, Biochemistry, Biotechnology, Cell Biology, Cell Culture Techniques, Cell Transfection, Chemical Engineering, Data Analysis, Detail-Oriented, Flow Cytometry, Immunochemistry, Immunocytochemistry (ICC), In Vitro Assays, Lab Equipment Maintenance, Laboratory Maintenance, Luminex Assays, Microbiology, Molecular Biology Techniques, Monoclonal Antibodies, Parasitology

Preferred Skills:

Working in a related industrial setting

Knowledge and experience with different recombinant protein expression system at industry scale

Experience in the downstream process development for therapeutic monoclonal antibodies produced from commercial CHO cell line.

The salary range for this role is $87,300.00 – $137,400.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status: Regular

Relocation: No

VISA Sponsorship: No

Travel Requirements: 10%

Flexible Work Arrangements: Not Applicable

Shift: 1st – Day

Valid Driving License: No

Hazardous Material(s): n/a

Job Posting End Date: 03/9/2026

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.