Scientist I, Cell Culture Process Development Full-time

Job Title

We are seeking an enthusiastic and creative hands-on scientist to join the Cell Culture Process Development group within PDS&T Biologics at AbbVie Bioresearch Center in Worcester, MA.

Job Description

As part of the Cell Culture Development organization, you will support process development and technology transfer activities for cell culture processes, contributing to the clinical manufacturing and commercialization of therapeutic proteins in the AbbVie pipeline. Additionally, the team provides subject matter expertise and experimental support for the production of commercial biologics. The ideal candidate will work effectively both independently and collaboratively within a dynamic team environment.

Key Responsibilities

Develop and characterize highly-productive CHO cell culture processes suitable for cGMP biotherapeutic manufacturing within project timelines, performing technical transfer and manufacturing support activities.

Conceive and execute scientific research and development to significantly improve platform processes and workflows, develop new methods, build technical expertise and deepen scientific understanding.

Design, execute and analyze cell culture experiments using Design of Experiments (DOE) principles and report data summary packages for multi-variate analysis.

Work collaboratively and cross-functionally with colleagues in other functional areas (Analytical Development, Cell Line Development, Discovery, Manufacturing and Quality).

Effectively communicate scientific data and concepts to internal and external audiences through reports, presentations and manuscripts.

Author and review technical reports, protocols, and other key documents.

Understand and adhere to corporate standards regarding code of conduct, safety, documentation and GMP compliance.

Preferred Qualifications

M.S. in biology, biochemical/chemical engineering or life sciences related disciplines with 2+ years of industrial experience; or B.S. in biochemical/chemical engineering or life sciences related disciplines with 5+ years of industrial experience.

Hands-on experience with upstream mammalian suspension cell culture using bench scale bioreactors, deep well plates and shake flasks.

Understanding of cell culture processes (e.g., cell culture process development, process scale up and scale down, recombinant protein production, protein characterization).

Experience with statistical data analysis tools such as design of experiment, multivariate data analysis and modeling.

Experience with automated liquid handling systems and high throughput culture is a plus.

Excellent interpersonal and communication skills. Strong scientific curiosity with a passion for problem-solving and optimization. Self-motivated with excellent attention to detail and ability to multi-task. Strong organizational, planning and trouble-shooting skills.

Qualifications

Bachelor's Degree or equivalent education with typically 5 years of experience, or Master's Degree or equivalent education with typically two years of experience.

Theoretical and practical knowledge to carry out the job functions.

Additional Information

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

This job is eligible to participate in our short-term incentive programs.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only – to learn more, visit Equal Employment Opportunity Employer

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: Reasonable Accommodations

Recruitment Fraud Alert

We have recently become aware of various recruitment phishing scams targeting job seekers. Please be advised:

AbbVie will never request sensitive personal information (such as bank account details, social security numbers, or payment of any kind) during the recruitment process.

If you suspect you have received a fraudulent offer or communication claiming to be from AbbVie, please do not respond, open any attachments, or click on any hyperlinks.

If you have any questions or concerns regarding the authenticity of a communication alleged to have been made by or on behalf of AbbVie, please contact us immediately.

Protect yourself by verifying job offers and communications. Your safety is important to us.