Scientist II, Analytical Development Full-time NEW

Scientist II, Analytical Development

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience – and products and services in our Allergan Aesthetics portfolio.

We seek a Scientist II, Analytical Development to join an experienced, fast-paced and collaborative team. This position will be primarily responsible for supporting characterization of AbbVie's mRNA-based targeted lipid nanoparticles (tLNPs) pipeline. This role will focus on executing testing methods for characterizing mRNA/tLNPs and supporting development of new tLNP characterization methods. Working collaboratively across the discovery research team, this position will support process/product characterization, expansion of the mRNA/tLNP pipeline, method development, and platform development.

Responsibilities & Duties:

• Independently perform HPLC, CE, and plate-based assay testing of mRNA and tLNP products for characterizing content, purity/impurities, and integrity
• Support development of novel nanoparticle characterization techniques, including but not limited to MALLS, mass photometry, etc
• Re-optimize analytical methods to support new programs and platform improvements
• Improve routine assay efficiency through automation and assay/workflow improvements
• Author technical reports and documents as needed

Qualifications:

• Generally met with a Master's with 5+ years experience or Bachelor's with 7+ years of experience
• Degree in Biochemistry, Chemistry, Bioengineering, Chemical Engineering or related field with experience testing and developing analytical characterization methods for biologics (e.g. antibodies, mRNA, etc) is required
• Experience with nanoparticle and/or small molecule characterization is preferred
• Experience with HPLC, Capillary Electrophoresis (CE), and plate-based assays required
• Proficiency authoring and reviewing technical reports
• Experience with stability and comparability studies is preferred
• Strong communication skills, both written and verbal, with a demonstrated capacity to thrive in collaborative, team-driven environments.

Pay Range: $84500 – 162000 USD

Role is exclusively performed at a site or office and onsite presence is required. Employees who are site/office-based and can occasionally perform their role virtually work both in the office and remotely*, following the policies and regulations in place at their location. US Employees must be in the office on Tuesday, Wednesday, and Thursday with flexibility to work remotely on Mondays and Fridays. Three days in the office is the minimum; some individuals or teams may require more in-office days due to meetings, business/project needs or their role.