Scientist II, Brain Transport Biology Full-time

Job Title

The Discovery Neuroscience In Vivo Pharmacology group in Cambridge, Massachusetts, is seeking a highly skilled and self-motivated scientist to join a dynamic team supporting target identification, validation, and drug transport facilitation over brain barriers. The ideal candidate will have strong hands on experience with various ex vivo analysis techniques including biochemistry and qPCR.

Key Responsibilities

Responsible for design and implementation of ex vivo analysis of tissue samples from in vivo studies testing multispecific biologics, small molecules, and siRNAs to support projects in the areas of Alzheimer's and Parkinson's disease. Identify and solve technical problems independently, implement new assays and workflows, conceive and implement innovative research ideas. Ensure consistency and quality of technical reports. Present original work internally across departments.

Qualifications

Minimum Qualifications:

• BS or equivalent education with typically 7 or more years of experience or MS or equivalent education with typically 5 or more years of experience. Degree in Neuroscience, Biological Sciences, Pharmacology, or related discipline preferred.
• Experience with ex vivo readouts including biochemistry (ELISA, WB), qPCR and immunohistochemistry
• Proven track record of working in multidisciplinary in vivo pharmacology teams
• Experience with in vivo models of neurodegeneration, particularly with models of Alzheimer's and Parkinson's Disease
• Proven track record in characterizing complex biotherapeutics in vivo (biologics, small molecules, siRNA)
• Excellent organizational skills and the ability to manage multiple studies simultaneously
• Candidate must be a goal-oriented team player with excellent verbal and written communication skills and strong “can-do” attitude

Preferred Qualifications:

• Experience with digital PCR and MSD assays
• Experience with image analysis

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.

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Travel: Yes, 5% of the Time

Pay Range: $78500 – 141000 USD