Scientist II, In Vivo Oncology Pharmacology Full-time

Oncology Pharmacology Scientist II

The in vivo Oncology Pharmacology group is seeking a highly motivated, organized, interactive, team-oriented Scientist II to join our Ridgefield, CT team. The successful candidate will develop and execute in vivo and ex vivo murine experiments in support of company drug discovery goals in an independent manner with thoughtful trouble shooting. The candidate will possess a thorough knowledge of experimental design, the underlying scientific concepts, and have the ability to document/communicate work clearly and concisely.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Duties & Responsibilities

• Design, plan and execute murine in vivo tumor experiments in an independent manner to achieve defined objectives. Independently initiate and carry out the studies after receiving alignment from manager.
• Key in vivo skills include animal handling and multiple dosing routes.
• Design and execute in vitro and ex vivo assays such as ELISA, MSD, and cell culture.
• Experience performing 8-16 color flow cytometry to characterize immune populations and changes after pharmacological intervention
• Draws conclusions from experiments and applies knowledge to interrogate target biology. Independently initiates and rapidly executes next steps.
• Effectively communicate, document, and maintain meticulous experimental results and protocols in electronic workbooks.
• Present experimental results and conclusions at team and cross-functional meetings. May give oral presentations at external meetings.
• Collaborate within the team and work together to lend a hand for large in vivo studies

Requirements

• Bachelor's Degree with over 3 years of experience in a related scientific discipline, or a Master's Degree in a related scientific discipline, or equivalent experience in the field.
• Strong understanding of animal husbandry and in vivo mouse techniques: tumor implantation, tissue/organ isolation, IP, IV, SC, and oral dosing not under anesthesia. Basic mouse handling and necropsy.
• Basic understanding of immunology assays such as: Flow cytometry, tissue culture, primary immune cell culture, ELISA, RT-qPCR, transfections, and western blots.
• Knowledge in immunology and/or tumor immunology field
• Ability to work effectively in a highly collaborative research environment

Compensation: The base salary range for this position, Scientist II, is $75,000.00 and $122,000.00. The position may be eligible for a role specific discretionary bonus, relocation, and/or other compensation elements. We continuously review market data and may adjust salary ranges as needed in the future. Actual compensation will be based on job-related factors such as skills, experience, and qualifications, and other factors permitted by law.

• Must be legally authorized to work in the United States without restriction.
• Must be willing to take a drug test and post-offer physical (if required).
• Must be 18 years of age or older.