Scientist II, Protein Biology Full-time

Job Title

As part of the Thermo Fisher Scientific team, you'll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world's toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.

Join our collaborative Antibody Development team at Thermo Fisher Scientific, where you'll contribute to advancing protein and antibody engineering technologies. As a Scientist II in Protein Biology, you'll be part of our team focused on designing, developing, and validating high-quality antibodies using advanced tools and methodologies. You'll contribute to research that enables our customers to make the world healthier, cleaner, and safer.

In this role, you'll plan and execute experiments independently, driving product development from concept through validation. You'll utilize advanced protein characterization techniques while collaborating across teams to optimize workflows and improve product quality. The position offers opportunities to support junior scientists, present research findings, and contribute to scientific innovation in a supportive environment dedicated to excellence.

Nature Of Experience

• Masters degree with over 5 years relevant experience or PhD with greater than 2 years' experience in a life sciences field, plus 2 years of experience in protein purification and analysis using chromatography (affinity, ion exchange, SEC, HPLC)

Preferred fields of study: molecular biology, immunology, biotechnology, biochemistry, structural biology, protein design, or protein engineering.

• Extensive experience and familiarity with antibody or protein engineering, rational design, and molecular biology using tools and methodologies of structural biology and protein modeling and visualization tools such as Pymol, Shrodinger, Discovery Studio or other such programs.
• Experience in the field of molecular biology, protein expression, protein purification, and protein-protein interaction, protein structure -function relationships, and immunogen designs.
• Expertise in development of conjugation chemistries or performing antibody conjugations is desired
• Proficient in molecular biology workflows such as high-throughput molecular cloning, plasmid vector construction, PCRs, restriction digestion, ligation, transformation, mini and maxi preps, sequencing
• Thorough in biochemical and immunoassay workflows such as recombinant protein expression and purification, ELISA, SDS-PAGE, Western blotting, IF, IHC
• Ability to provide technical trouble shooting to resolve scientific problems.
• Proficient in software or platforms for molecular biology and sequence analysis, MS Office and statistical software such as GraphPad Prism.
• Authorship of peer-reviewed publications with post-doctoral experience and a strong, independent understanding of standard and emerging research protocols and techniques are preferred. GLP experience is a must.