Scientist III, Antibody Kinetics Biotherapeutics Full-time

Scientist III

Boehringer Ingelheim is currently seeking a talented and innovative Scientist III to join the Antibody Generation Group within the Biotherapeutics Department located at our US headquarters in Ridgefield, CT. This position will be responsible for designing, executing, and interpreting Surface Plasmon Resonance (SPR) experiments to characterize binding interactions and kinetics of biotherapeutic modalities, including antibodies and protein based therapeutics. This role applies advanced kinetic data analysis to inform lead selection, affinity maturation, and developability assessments in biotherapeutic discovery programs. This individual will be expected to make major contributions to the generation of best-in-class and first-in-class therapeutics to address major unmet medical needs.

Contributes to R&D discovery research by performing scientific research. Implements protocols as required. Provides expertise within a technical specialty required for skill center productivity.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Duties & Responsibilities

• Independently design, execute, and interpret SPR experiments to characterize antibody–antigen interactions, providing scientifically rigorous kinetic data that supports biotherapeutic discovery and departmental research goals. • Apply advanced kinetic modeling and data analysis to inform lead selection, affinity maturation, and mechanism of action hypotheses, clearly articulating experimental rationale, limitations, and impact to project teams and the broader discovery organization. • Contribute to the incorporation of new SPR methodologies, technologies, and best practices to enhance assay robustness, efficiency, and scientific impact, while proactively proposing innovative ideas and challenging existing workflows. • Support laboratory excellence by assisting in the training and mentoring of junior scientists, sharing expertise beyond the immediate group, and helping streamline laboratory processes to improve effectiveness and data quality. • Collaborate closely with cross functional discovery teams to deliver high quality, data driven insights that advance candidates toward development. • Complies with applicable regulations, performing all work in a safe manner; Maintains proper records in accordance with SOPs and policies.

Requirements

• Master's degree in a related scientific discipline with 6+ years of industry experience or equivalent experience in molecular/cellular biology or biochemistry. • Requires working knowledge of SPR-based technologies and the application of this technology in the drug discovery process to support project efforts, ranging from hit identification to mechanism- of-action studies. • Expert level knowledge of assay development methodologies for SPR specific instrumentation (BiacoreT200/S200, Biacore8K) supported by hands-on experience. (LSA-XT experience a plus) • Extensive experience performing assay data capture and analysis using software such as, Biacore Insight, Spotfire, and Prism. • Ability to work within a collaborative team environment and present and defend results to project and technical teams.

Eligibility Requirements:

• Must be legally authorized to work in the United States without restriction. • Must be willing to submit to a background investigation, including verification of your past employment, criminal history, and educational background. • Must be willing to take a drug test and post-offer physical (if required). • Must be 18 years of age or older.

Compensation Data

This position offers a base salary typically between $115,000 and $181,000. The position may be eligible for a role specific variable or performance-based bonus and or other compensation elements. For an overview of our benefits please click here.