Scientist, Oncology Translational Research Full-time

Scientist, Oncology Translational Research

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

The Oncology Thematic Research Center at BMS is a key research and early development engine, responsible for the discovery and development of novel oncology therapeutics for patients. Centered at our state-of-the-art research sites in Cambridge and Seattle, scientists focus on novel targets and pathways for tumors that are refractory to current therapies. With a deep understanding of the causal human biology, we are able to leverage our multiple modality platforms to best match the modality to the mechanism and desired outcome. We are a fully integrated drug discovery through translational and early clinical development organization which exploits state-of-the-art in vitro, in vivo and ex-vivo models of Cancer biology and Immuno-oncology to identify and validate targets. We partner closely with colleagues in Translational Medicine, Informatics and Predictive Sciences and Early Clinical Development to generate biomarker and patient enrichment hypotheses to enable efficient decision making in early clinical trials. We are optimally positioned to complement the world-class translational expertise, biology and leading academic research centers in the area.

Our Bristol Myers Squibb research site in Cambridge Crossing will help us continue to deliver on our mission, positioning the company and our scientists in the heart of a vibrant ecosystem of world-class science, innovation, and business opportunities.

Position Summary

We are seeking an individual with oncology research experience to join the Translational Research team within the Oncology Thematic Research Center at Bristol Myers Squibb in Cambridge, MA. The qualified candidate is a highly motivated, engaged, and organized scientist that can thrive in a highly matrixed organization. This role will support translational research lab-based activities from the stage of development candidate optimization through Proof-of-Concept clinical trials. This individual will play an important role in supporting the development and execution of translational strategies for early phase oncology assets, enabling the development of transformative cancer therapies for patients.

Position Responsibilities

In the role as a Scientist within Oncology Translational Research, the ideal candidate will:

• Develop biomarker, pharmacodynamic and target engagement assays.
• Use current and new techniques to characterize drug mechanism of action and resistance.
• Have familiarity with commonly utilized in vitro oncology and cancer immunology models and assays.
• Experience performing laboratory work, including cell culture and isolation of primary immune cells.
• Execute experiments independently, troubleshoot as needed, analyze, interpret and discuss data.
• Design and execute preclinical studies to inform indication selection, patient enrichment, rational combination strategies, and selection of biospecimen collection timepoints
• Have excellent time management skills and the ability to conduct experimental work independently, with accurate, detailed record-keeping.
• Display excellent communication, presentation and interpersonal skills.

Experience = Basic Qualifications

• Bachelor's Degree with 5+ years of academic and / or industry experience.
• Master's Degree with 3+ years of academic and / or industry experience.
• Ph.D. or equivalent advanced degree in the Life Sciences with no experience required.

Preferred Qualifications

• Bachelor's or Master's Degree with 5+ years of industry experience. Oncology translational research experience is highly desired.
• Experience in oncology and cancer immunology.
• Proficient in translational research encompassing biomarker identification, PK/PD and efficacy correlations, and dose estimation
• Experience designing and validating novel biomarker assays for proof-of-concept, suitable for deployment in early-phase clinical trials.
• Collaborate closely with fellow translational research scientists, actively sharing expertise and ensuring smooth information exchange across programs and portfolios to strengthen teamwork and drive scientific advancement.
• Experience performing analysis of protein, DNA, and RNA samples using a variety of methodologies including but not limited to: flow cytometry, MSD/ELISA, Western blot, qPCR, and functional assays.
• Ability to effectively collaborate with internal and external partners (e.g. CROs, specialty labs, etc.)
• Ability to be flexible with changing priorities while working in a cross functional team.

Compensation Overview:

Cambridge Crossing: $129,640 – $157,096

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.

Work-life benefits include:

• Paid Time Off
• US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
• Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com.

Candidate Rights

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

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