Scientist – Protein Biochemistry Full-time NEW

Scientist

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.

We believe the Greater Boston area is an important hub for the biotech and pharma industry, which is why we've invested in growing our footprint and expanding our R&D space in Cambridge, with a primary focus on additional state-of-the-art lab space. Here, we will bring together talent and expertise, building upon GSK's long history of vaccine development, to create globally leading viral capabilities and cutting-edge vaccines technologies, as we add to our robust portfolio targeting infectious diseases at every stage of life.

As a Scientist, you will be expected to use your knowledge of biochemistry and biophysics to independently design and execute experiments with guidance from the lab head and project teams. You must be self-motivated to deliver vaccine program objectives on time and be able to identify and mitigate any potential delays.

Key Responsibilities:

• Apply biochemistry and biophysics expertise to the design and development of GSK vaccine projects.
• Implementation of new technologies to help drive vaccine development.
• Perform high throughput screening and purification of recombinant soluble proteins, membrane proteins, mAbs, and viral like particles.
• Develop and conduct assays to evaluate the biophysical properties of the vaccine candidates.
• Possesses strong scientific leadership to enable collaboration with key scientific internal and external stakeholders.
• Publish in peer reviewed journals.

Basic Qualifications:

• PhD with 0+ years of post-doc and/or job-related experience, MS with 3+ years of experience, or BS with 6+ years of experience.
• Three or more years of experience on a wide variety of molecules such as recombinant soluble proteins, membrane proteins, mAbs, and viral like particles.
• Three or more years of hands-on experience on protein purification utilizing affinity purification, anion exchange, and size exclusion chromatography.
• Three or more years of hands-on experience on biophysical techniques including Octet/SPR, DLS, nano-DSF, CPS-Disc, HPLC, UPLC, and protein stability assays.

Preferred Qualifications:

• Prior experience with one or more of the following:

  • Working with PyMOL to observe and analyze structures.
  • Experience on Negative scan electron microscopy.
  • Collaborating with large project teams in a matrix environment.
  • Excellent communication skills to effectively convey complex scientific data.
  • Basic skills in statistical analysis.

This position requires on-site attendance five days a week in Cambridge, MA.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.