Scientist/Senior Scientist (JG Lab), IMCB Full-time

Scientist/Senior Scientist (JG Lab), IMCB

Conduct affinity maturation and enzyme engineering using integrated dry-lab (in silico) and in vitro approaches.

Design and execute selection strategies, including assay development, to support lead asset characterization, prioritization, and optimization.

Perform and analyze protein-protein binding and enzyme kinetics data to guide iterative optimization cycles.

Transitioning to lead proteomics-driven experiments to identify novel biomarkers and validate their therapeutic druggability.

Prepare presentations, reports, and documentation, support training of junior staff and other assigned research duties.

PhD in Protein Engineering, Biochemistry or a related life sciences field.

Experience in binding/kinetic assays, affinity maturation and/or enzyme engineering, computational protein design, sequence analysis and variant prioritization.

Understanding of protein-protein interactions, enzyme kinetics, and developability considerations.

Ability to work collaboratively in interdisciplinary teams and communicate scientific results effectively.

1-2+ years of postdoc experience in the above areas is a plus.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.