Scientist/Senior Scientist (Lipidomics), A*SRL Full-time

Scientist/Senior Scientist (Lipidomics), A*SRL

The A*STAR Skin Research Labs (Skin Omics group) is seeking a Scientist or Senior Scientist with expertise in metabolomics and lipidomics to lead and support analytical research on skin metabolism. The successful candidate will work with state-of-the-art LC-MS platforms to profile, quantify, and interpret lipid and metabolite signatures from skin and microbiome systems, contributing to the discovery of novel bioactive compounds and metabolic pathways.

Roles and Responsibilities:

• Design, develop the method, optimise and execute metabolomics and lipidomics experiments using LC-MS/MS techniques (targeted and untargeted).
• Perform data processing, statistical analysis, and metabolite identification using specialised software tools.
• Interpret complex lipidomic datasets to elucidate biochemical mechanisms relevant to skin biology.
• Collaborate with cross-functional teams including biologists and chemists to integrate findings with molecular and phenotypic data.
• Maintain and troubleshoot analytical instruments (LC-MS, UPLC, etc.) and ensure quality control in data acquisition.
• Contribute to scientific writing, reports, publications, and presentations.

Job Requirements:

• PhD in Chemistry, Biochemistry, Analytical Chemistry, or related discipline.
• Strong expertise in metabolomics or lipidomics, with demonstrated experience in LC-MS-based workflows.
• Hands-on experience in data analysis using software such as Compound Discoverer, XCMS, or similar platforms.
• Solid understanding of lipid biochemistry and metabolic pathways.
• Excellent analytical, problem-solving, and communication skills.
• Ability to work independently and collaboratively in a multidisciplinary research environment.
• Proven track record in lipidomics or bioanalytical method development.
• Experience in quantitative metabolomics, stable isotope tracing, or MS imaging would be an advantage.