Senior Associate Scientist Full-time

Senior Associate Scientist

At Sanofi we are committed in our quest to be a world-class biologics research organization and are steadfast in our goal to bring next generation, transformative therapies to patients. Our global Large Molecule Research (LMR) organization is focused on antibodies and NANOBODY® molecules as therapeutic modalities. Our platform enables and partners closely with other research platforms and Sanofi's therapeutic areas (Immunology & Inflammation, Immuno-Oncology, Rare & Neurologic Diseases) in the discovery and ultimate delivery of new candidate molecules.

We are seeking a talented and highly motivated Senior Associate Scientist to join our dynamic team in the Molecular, Expression and Screening Technologies (MEST) Group within Sanofi's North America R&D LMR organization. The lab-based candidate will be responsible for the ultra-high-throughput expression of protein/antibody tools and therapeutic candidates designed by state-of-the-art digital AI/ML models and structural biology using cutting-edge automated systems. The candidate will work closely with other functional groups in MEST as well as LMR (Antibody Discovery, Protein Production and Protein Engineering) to discover new therapeutic antibodies. The focus of this position is on the day-to-day operation of high-throughput protein production systems including scheduling software, maintenance and troubleshooting of this system and its components. Experience with mammalian cell culturing, maintenance and expansion of cell lines as well as the transfection of mammalian cells using recombinant DNA are key. The demand for production of complex variants has significantly increased year on year, with additional increases expected.

Join the engine of Sanofi's mission — where deep immunoscience meets bold, AI-powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions.

We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.

Main Responsibilities

• Operate and maintain high-throughput automated protein production systems, including liquid handlers (Tecan/Hamilton) and integrated scheduling software
• Execute transient mammalian protein expression workflows at scale, including plasmid preparation, mammalian cell transfection using recombinant DNA, and cell line maintenance and expansion
• Manage and troubleshoot automated instrumentation to ensure optimal performance and minimal downtime
• Utilize GeneData Biologics and other biological registration systems for accurate data entry, sample tracking, and production management
• Analyze and interpret large-scale production datasets using tools such as Spotfire and R (statistical programming) to support AI/ML model inputs and research decisions
• Develop and maintain R-based scripts and workflows for data processing, visualization, and reporting of high-throughput experimental results
• Present findings and technical updates clearly and concisely to diverse scientific audiences
• Collaborate effectively with cross-functional teams to meet production goals and research timelines

About You

Basic Qualifications:

• BS or MS in Biology, Biochemistry, Molecular Biology, or a related field
• Proven hands-on experience in a research laboratory or biopharma/biotech environment
• Proven experience operating high-throughput automation and liquid handling systems (Tecan, Hamilton, or equivalent)
• Hands-on expertise in transient mammalian protein expression and mammalian cell culture techniques
• Proficiency in GeneData Biologics or equivalent biological registration systems
• Experience analyzing and transforming large datasets using Spotfire, R, and/or similar analytical tools
• Proficient in Microsoft Excel and the broader Microsoft Office suite
• Exceptional attention to detail with strong organizational, time management, and teamwork skills

Preferred Qualifications:

• Background in Molecular Biology, including plasmid construction and cloning techniques
• Familiarity with AI/ML-driven research workflows in a biopharma setting
• Experience with scheduling software for automated production systems

Why Choose Us

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.
• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.
• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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