Senior Associate Scientist – Viral Vaccines & Immunology Full-time NEW

Senior Associate Scientist Biology

At Pfizer, our purpose is to deliver breakthroughs that change patients' lives. As a Senior Associate Scientist Biology, you will be at the forefront of our mission, contributing to the development of innovative therapies and vaccines that have the potential to transform patient care. Reporting to the Research & Development division, you will leverage advanced science and cutting-edge technologies to make a tangible impact on global health. Your work will be instrumental in ensuring drug safety and efficacy, supporting clinical trials, and accelerating the delivery of top-tier medicines to patients worldwide.

In this role, you will:

• Conduct various assays to monitor immune responses elicited by vaccine candidates and document laboratory work involving bio-functional assays thoroughly.
• Maintain cell lines, process red blood cells weekly, and prepare samples for testing, assisting with molecular and virology work.
• Generate plasmid constructs for RNA and reverse genetic virus stocks, optimizing RNA vaccines.
• Ensure compliance with SOP guidelines, cGLP, and/or cGMP guidelines, and execute qualifications and validations of new instruments and custom methods.
• Contribute to work group goals, collaborate with team members, and participate as a team member.
• Prioritize work to meet project deadlines, apply technical skills to assignments, and organize work according to departmental priorities.
• Choose between alternatives to solve moderately complex problems, follow procedures with general instructions, and work under moderate supervision with regular review.
• Collaborate with the Primary Pharmacology Group to ensure alignment around assay technology selection, assay quality criteria, and validation requirements.
• Interact with external vendors to obtain quotes and purchase reagents for clinical testing, and manage manual and robotic sample preparation.
• Identify and report experimental problems, troubleshoot causative factors, implement necessary corrections after discussing with the supervisor, and train other analysts on established technologies while managing direct reports.

Qualifications

Must Have

• BA/BS with at least 2 to 4 years of experience or MBA/MS with 0 to 3 years of experience.
• Hands-on experience in cell culture and cell-based assays.
• Proficiency in using relevant software for data analysis.
• Fundamental laboratory skills, including quantitative-PCR, molecular biology, western blotting, biochemical assays, and tissue processing.
• Strong background in experimental design and result interpretation.
• Effective verbal and written communication skills.
• Proficiency in using personal computers for word processing, Excel, PowerPoint, and scientific software.

Nice to Have

• Hands-on experience with mammalian cell culture and flow cytometry.
• Practical knowledge in cell culture techniques and flow cytometry analysis.
• Experience in drug discovery processes.
• Expertise in maintaining and manipulating cell lines for experimental purposes.
• Proficiency in analyzing cell populations and their characteristics.
• Strong problem-solving skills.
• Ability to work collaboratively in a team environment.
• Excellent organizational and time management skills.

Physical/Mental Requirements

• Basic laboratory training in aseptic technique is essential.
• Ability to work with infectious agents safely.
• Standard laboratory conditions and computer work– sitting, standing.
• This position may require the ability to stand and reach inside the hardware environment of various laboratory robotic equipment.
• Math skills for basic laboratory calculations.

Non-Standard Work Schedule, Travel or Environment Requirements

Work Location Assignment: On Premise

The annual base salary for this position ranges from $66,500.00 to $110,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.