Senior Data Scientist- Oncology Full-time

Senior Data Scientist- Oncology

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Johnson & Johnson Innovative Medicine is recruiting for a Senior Data Scientist- Oncology to join our Data Science and Digital Health team (DSDH). This position will be located at one of our offices in either Spring House PA (preferred), Cambridge MA, or San Diego CA (La Jolla area). Consideration may be given for our Titusville and Raritan, NJ locations.

The Senior Data Scientist- Oncology will design, build, and govern the semantic backbone that connects data across pharmaceutical life cycle. In this role, you will translate business concepts into well-formed ontologies, controlled vocabularies, and semantic standards that power interoperability, search and discovery, analytics, and AI/ML. The role combines hands-on ontology engineering with product thinking, partnering closely with governance, knowledge management, and domain stakeholders. The Senior Data Scientist is a leading technical contributor and creative problem solver with a strong background in semantic technologies, ontology, graph-based data modeling, and a deep understanding of the life sciences domain.

Key Responsibilities:

• For Oncology R&D data domains, model, code, test, and release ontology modules and mappings that power knowledge graph, master/reference data, analytics, and AI/LLM applications.
• Translate domain knowledge from Oncology & subject-matter experts in related disciplines into OWL/RDF classes and properties, SKOS vocabularies, and SHACL constraints, and publish validated, versioned packages and APIs for broad reuse.
• Participate in a wider community of scientists standardizing biomedical data across R&D aimed at increasing AI Readiness of a broad range of data domains
• Maintain accountability for selected Oncology R&D ontology roadmap for key domains – define scope, use cases, and success metrics; align with internal canonical models and relevant W3C/domain standards.
• Model and govern the ontology using (OWL, RDFS, SKOS, SHACL); capture provenance and maintain SPARQL queries with validation.
• Adhere to standards—modeling guidelines, naming/versioning, change control, releases/deprecations—and partner with enterprise governance/tooling teams to embed reusable patterns for product teams and consumers. Play a role in developing these standards as appropriate.
• Implement data quality checks (coverage, conformance, unit/ID normalization) and contribute to validation reports.

Preferred Qualifications:

• Desired Ph.D. or master's degree in bioengineering, computer science, IT, bioinformatics, physics, mathematics, or related fields, emphasis on semantic technologies and biomedical application.
• 3-5+ years of hands-on ontology/knowledge modeling, taxonomy design, and metadata standards.
• Proficiency with OWL, RDF(S), SKOS, SHACL, SPARQL, ontology design patterns and reasoning concepts.
• Familiarity large-scale knowledge graphs construction, ontology development and pharmaceutical or healthcare domains integration.
• Proficiency in semantic web technologies (SPARQL, RDF, OWL), familiarity with graph databases (Neo4j, Amazon Neptune, GraphDB).
• Experience in CI/CD implementations, git usage, CI/CD stacks (Jenkins, GitLab, Azure DevOps), DevOps tools, metrics/monitoring, and containerization technologies (Docker, Singularity).
• Strong skills in analysis, problem-solving, organizational change, project delivery, and managing external vendors.
• Proven record leading improvement initiatives with multi-disciplinary and remote partners.
• Demonstrated stakeholder management capabilities- including requirements gathering, business analysis and planning. Must have the capacity to translate discussions into user requirements and project plans.
• Ability to manage a numerous projects simultaneously, prioritize work, exhibit organizational skills and flexibility to deliver maximum business value.
• Willingness to conduct periodic travel (<15% of time) to conferences and internal meetings.

This position will be located at one of our offices in either Spring House PA (preferred), Cambridge MA, or San Diego CA (La Jolla area). Consideration may be given for our Titusville and Raritan, NJ locations. (No remote option.)

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via

The anticipated base pay range for this position is $109,000 to $174,800. The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/performance year. Bonuses are awarded at the Company's discretion on an individual basis. Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).

Employees are eligible for the following time off benefits:Vacation – up to 120 hours per calendar yearSick time – up to 40 hours per calendar yearHoliday pay, including Floating Holidays – up to 13 days per calendar year of Work, Personal and Family Time – up to 40 hours per calendar yearAdditional information can be found through the link below.

The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market.

Required Skills: Advanced Analytics, Business Intelligence (BI), Coaching, Collaborating, Critical Thinking, Data Analysis, Database Management, Data Privacy Standards, Data Reporting, Data Savvy, Data Science, Data Visualization, Econometric Models, Process Improvements, Technical Credibility, Technologically Savvy, Workflow Analysis

Preferred Skills: Advanced Analytics, Business Intelligence (BI), Coaching, Collaborating, Critical Thinking, Data Analysis, Database Management, Data Privacy Standards, Data Reporting, Data Savvy, Data Science, Data Visualization, Econometric Models, Process Improvements, Technical Credibility, Technologically Savvy, Workflow Analysis