Senior Immunology Scientist, Translational Immunosafety & Safety Biomarkers Full-time

The Position

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

In Roche’s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicine. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

This position is located in Pathology and Applied Safety Science, a chapter within the Pharmaceutical Sciences function, which enables portfolio decisions through integrative immunosafety, investigative safety and pathology expertise. We closely collaborate with our therapeutic areas and functions to convert hypotheses into innovative therapeutics.

The Opportunity

The Immunosafety team is seeking an experienced Immunologist focused on Translational Immunosafety, Safety Biomarkers, and Immunosafety Project Support. This role is crucial for expanding our presence in Translational Immunosafety & Safety Biomarkers to meet the evolving demands of our portfolio.

• You develop strategies to bridge preclinical findings to clinical settings, informing clinical trial design, patient selection, and monitoring.
• You provide comprehensive Immunosafety project support across the drug development value chain.
• You identify and characterize new safety biomarkers for immune-related adverse events (e.g., immunotoxicity, cytokine release syndrome (CRS), autoimmunity).
• You provide immunological insights for integrated risk assessment of drug candidates and contribute to risk mitigation strategies.
• You develop, optimize, and validate immunological assays, applying expertise in in vitro and in vivo immunological models, including New Approach Methodologies (NAMs), and other new technologies.

Who You Are

• You bring a PhD in Immunology, Toxicology or a related field with > 5 years of experience in drug development.
• You have expertise in translational immunosafety, including safety biomarker discovery and development.
• You bring expertise in tissue-specific immunology and application in a mechanistic toxicology environment in the context of immunocompetent in vitro models, is a plus.
• You are proficient in immunological assays, immunocompetent in vitro models, and model development and validation (in vitro, in vivo, and NAMs).
• You can provide immunological insights for risk assessment and mitigation.
• You are experienced in providing project support within a drug development setting.

Unwavering focus, collaborative teamwork and exceptional delivery are key behaviours that drive our mission of doing now what patients need next. Together, we can be transformative.

If you are passionate about contributing to a committed team and have the dedication to partnership and innovation, Roche is the place for you! Every role at Roche plays a part in making a difference in patients’ lives.

Apply now and join us in making an impact!