Senior Principal Scientist, BioTherapeutics Process Development Full-time

Senior Principal Scientist, BioTherapeutics Process Development

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.

We are searching for the best talent for a Senior Principal Scientist, BioTherapeutics Process Development to be onsite in Malvern, PA.

Purpose: The API Upstream Process Development Group is searching for a highly qualified and accomplished individual to join the API Upstream Process Development team as a Senior Principal Scientist.

You will lead development and implementation of cell-biology based computational methodologies to optimize biotherapeutic processes and cell culture media. You will be part of CMC team(s) and play a significant role in successful delivery of project deliverables. This position is highly cross functional and will require intellectual agility and interpersonal skills to work across different modalities, e.g., project teams, analytical, statistical, cell biology, and data scientists.

You will be responsible for:

• Advancing pipeline by collaborating with multi-functional teams, including bioprocess engineers, analytical scientist, and statisticians
• Participating or leading process optimization, characterization, and/or tech transfer & scale up/down workflow
• Serving as a scientific leader in metabolic pathways-based analysis (e.g. MFA/FBA)
• Developing and embedding advanced data analytics tool for cell culture & media optimization
• Contributing to strategic initiatives
• Mentoring and upskilling workforce

Qualifications / Requirements:

Education: Bachelor's degree is required. Master's degree or PhD in Chemical Engineering, Cell Biology, Biochemistry or related fields is highly preferred

Required:

Minimum 8-10 years of biotech/pharmaceutical industry and academic experience

In-depth knowledge of industrial bioprocessing, cell culture, cell biology, and/or system biology

Expertise in programming languages such as Python, R, or MATLAB, and experience with relevant packages and software tools

Expertise in mathematical/computational approaches for metabolic pathways (e.g. MFA/FBA)

Strong project and technical leadership skills demonstrated by successful management and delivery of CMC deliverables

Excellent communication and collaboration skills, with the ability to work effectively in a multidisciplinary team

Good written and oral communication skills

Preferred:

Hands-on experience with industrial CMC process development

Experience/in-depth knowledge of model-based regulatory filings

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center or contact AskGS to be directed to your accommodation resource.