Senior/Research Fellow [LKCMedicine] Full-time

Senior/Research Fellow Position

The Lee Kong Chian School of Medicine (LKCMedicine) trains doctors who put patients at the centre of their exemplary care. The School, which offers both undergraduate and graduate programmes, is named after local philanthropist Tan Sri Dato Lee Kong Chian. Established in 2010 by Nanyang Technological University, Singapore, in partnership with Imperial College London, LKCMedicine aims to be a model for innovative medical education and a centre for transformative research. The School's primary clinical partner is the National Healthcare Group, a leader in public healthcare recognised for the quality of its medical expertise, facilities and teaching. The School is transitioning to an NTU medical school ahead of the 2028 successful conclusion of the NTU-Imperial partnership to set up a Joint Medical School. In August 2024, we welcomed our first intake of the NTU MBBS programme, that has been recently enhanced to include themes like precision medicine and Artificial Intelligence (AI) in healthcare, with an expanded scope in the medical humanities. Graduates from the five-year undergraduate medical degree programme will have a strong understanding of the scientific basis of medicine, with an emphasis on technology, data science and the humanities.

The Nutrition, Digestion and Metabolism Lab in A/Prof Sunny Wong's group focuses on translational research in gastrointestinal diseases, particularly colorectal and gastric cancer, as well as metabolic disorders. The lab studies the interplay between diet, metabolism, and the microbiome, integrating clinical cohorts, microbiome profiling, multi-omics technologies, and experimental models to better understand disease mechanisms.

The team aims to translate fundamental research findings into meaningful clinical applications by identifying microbiome-related biomarkers for early detection, risk stratification, and treatment response, and by exploring new therapeutic strategies to improve patient outcomes.

We are looking for a Senior/Research Fellow to contribute to translational research in gastric cancer and microbiome science. The role will focus on investigating host-microbiome interactions, molecular mechanisms of carcinogenesis, and biomarker development through the integration of clinical cohorts, laboratory studies, and multi-omics analyses.

Key Responsibilities:

• Conduct in vitro and in vivo experiments to investigate mechanisms relevant to gastric cancer and microbiome-related research
• Perform microbiome profiling and molecular analyses
• Perform bioinformatics and integrative multi-omics analyses to identify perturbed pathways, molecular signatures and clinically relevant biomarkers
• Contribute to translational research activities, including processing and analysis of clinical specimens from patient cohorts
• Prepare scientific manuscripts, research reports and grant applications, and present findings at national and international conferences
• Provide mentorship and supervision to undergraduate, postgraduate and junior research personnel
• Collaborate with clinicians, bioinformaticians and interdisciplinary research teams to achieve project milestones and scientific objectives
• Maintain compliance with institutional, ethical, and biosafety regulations in all research activities

Required educational qualification, experience, skills and competencies:

• PhD degree in Biological Sciences, Microbiology, Cancer Biology, Molecular Medicine or related field
• At least 2 years of relevant experiences in similar role with hands-on expertise in microbiome research, molecular biology
• Familiarity with translational research methodologies and ethical guidelines related to clinical and/or animal studies
• Experience in data analysis and bioinformatics
• Good written and oral communication skills
• Strong organizational skills and ability to work independently under strict timelines
• Ability to work collaboratively in a multidisciplinary research environment

Hiring Institution: LKC