Senior Scientist, Antibody and Protein Engineering Full-time

Senior Scientist

We are seeking a highly motivated and results-driven Senior Scientist to join our fast-paced and innovative Bispecifics & Antibody Engineering Department. You will be part of a group of diverse talents responsible for the design, production and characterization of next-generation antibody and protein therapeutics for infectious disease targets at Regeneron. This position will have a direct impact in innovative platform development at this exciting time, as significant advancements in antibody engineering has already propelled approvals of multiple next-gen antibody-based therapies in many indications.

As a Senior Scientist, a typical day may include the following:

1. Apply molecular and structural biology expertise to design innovative bi- and multi-specific antibodies with improved potency, selectivity and developability.
2. Produce novel alternative format antibodies through mammalian expression and purification.
3. Perform and troubleshoot in vitro bioanalytical and cell-based assays (SDS-PAGE, western blotting, flow cytometry binding, ELISA, qPCR).
4. Collaborate with stakeholders in Infectious Disease to align on engineered antibody designs, research objectives, and next steps.
5. Effectively communicate results to management and stakeholders in group and departmental meetings and maintain timely records in electronic lab notebooks.

This role may be for you if:

• You are results-driven, can learn new skills quickly, and demonstrate a strong track record of troubleshooting assays.
• You have a background in infectious disease and antibody engineering.
• You are experienced in molecular biology and protein production.
• You have strong organizational, communication, and presentation skills.
• You enjoy working collaboratively in teams with diverse backgrounds and can handle multiple projects simultaneously.

To be considered for this role you must have a PhD in molecular biology, cell biology, biochemistry, or a related field, with at least 1 year of relevant experience in academia or industry. Desired candidates must have hands-on experience with cloning, antibody expression in mammalian cell lines, antibody purification (i.e., experience with AKTA) and biochemical/biophysical characterization. Familiarity with flow cytometry, neutralization assays, and/or structural biology is preferred but not required.

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!