Senior Scientist, Assay Development Full-time NEW

Senior Scientist, Assay Development

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

We are searching for the best talent for a Senior Scientist, Assay Development to be onsite in Cambridge, MA.

Purpose: The In Vivo Antibody Discovery group within Biologics Discovery is responsible for lead antibody generation from immunized animals with state-of-the-art technologies including single B cell sorting, hybridoma, display and microfluidics. As a member of the IVAD Group, this role will be responsible for the development and implementation of biochemical or cell-based binding and functional assays to support antibody generation against targets in different disease areas. In-depth knowledge and hands-on experience in assay development on Beacon microfluidics will be preferred. A strong understanding of cell biology and disease molecular pathways will also be important. This is a critical function in a multifaceted Biologics Discovery organization committed to bringing the next generation of biotherapeutic molecules to patients. We are looking for a motivated candidate with scientific and technical expertise who can collaborate across discovery areas to bring value to our portfolio of innovative drug concepts. Proficiency to work within a highly coordinated, fast-paced environment will be a significant attribute. An additional knowledge base in the areas of oncology, immunology, infectious disease, or cardiovascular disease would be a plus. If this sounds like you, come join our team!

You will be responsible for:

• Design and optimize biochemical/cell-based binding and functional assays with appropriate reagents for antibody screening
• Execute antibody discovery workflow on Beacon microfluidics platform to screen for functional antibody hits
• Evaluate animal serology using appropriate assays to select animals for screening
• Present research findings in internal meetings, clearly communicating scientific results and providing insights into data interpretation.
• Collaborate with multidisciplinary teams across functional areas to advance therapeutic programs in a dynamic and fast-paced environment.
• Document work accurately and promptly using Electronic Lab Notebook systems (e.g., Signal) and create detailed SOPs.

Qualifications / Requirements:

Education and Years of Experience:

• Minimum of a Bachelor's degree is required
• PhD in Molecular Biology, Biomedical Engineering, Biochemistry or a related field is highly preferred

Required:

• Minimum 4 years of experience in the pharmaceutical industry and/or academic setting
• Hands-on experience in assay development with expertise on protein-based binding assays and cell-based binding and functional assays
• In-depth knowledge on mAb, bi-specifics and multi-specifics as therapeutics
• Working knowledge on microfluidics-based antibody discovery platform (ideally Beacon)

Preferred:

• Assay development experience on microfluidics-based antibody discovery platform
• Flow cytometry expertise for single B cell sorting
• Experience or knowledge on generation of right reagents/cell lines for assay development on Beacon platform

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource.

The anticipated base pay range for this position is: $105,000-$169,050

Additional Description for Pay Transparency: Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits: Vacation – 120 hours per calendar year Sick time – 40 hours per calendar year; for employees who reside in the State of Washington – 56 hours per calendar year Holiday pay, including Floating Holidays – 13 days per calendar year Work, Personal and Family Time – up to 40 hours per calendar year Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child Condolence Leave – 30 days for an immediate family member: 5 days for an extended family member Caregiver Leave – 10 days Volunteer Leave – 4 days Military Spouse Time-Off – 80 hours Additional information can be found through the link below.