Senior Scientist, Cell Based Sciences Full-time NEW

Senior Scientist Cell Based Sciences Vaccines

The Analytical Research and Development team in West Point, PA is seeking an exceptional scientist who is passionate about innovative science and analytical solutions that enable and accelerate process and product development. The Senior Scientist within the department of Cell Based Sciences will join our vaccines team in West Point, PA.

The Senior Scientist will play a key role with the primary focus on the design, execution, and interpretation of method development, optimization, and transfer of cell-based assays and immunoassays for drug substance and drug product release, stability studies, and in-depth product characterization to support our vaccine pipeline. Responsibilities include building and implementing new assay platforms and benchmarking current approaches and techniques to the industry standards. These assays are expected to robustly reflect the mechanism of action (MoA) of vaccine candidates across the pipeline.

The successful candidate will be expected to work independently, communicate results effectively in presentations to stakeholders in partner organizations or at external scientific meetings, to author technical reports, to advise junior scientists, and to participate in cross-functional teams. The individual will enable and accelerate vaccine process development by applying cellular biology, virology, and immunology expertise.

The ideal candidate should have a deep understanding of relevant biological mechanisms and assay principles, and extensive experience with a broad range of methods and technologies used to access vaccine MoA and potency, with particular emphasis on cell-based assay and immunoassay development. Experience working in a GxP regulated laboratory environment (routine sample testing, documentation, and data verification) and experience with cell line engineering are highly desirable.

Position Qualifications:

• B.S degree with 6+ years of experience, M.S. degree with 4+ years of experience or Ph.D. degree in immunology, cell biology, bioengineering, biological sciences, biochemistry, virology, microbiology, or related field with experience in the biopharmaceutical industry.

Required Experience and Skills:

• Demonstrated experience in cell-based bioassay development for vaccines, with a deep understanding of mechanisms of action and assay principles.
• Scientific and technical expertise in cellular immunology and humoral / cell-mediated responses to vaccines.
• Hands-on experience with a range of biological, immunological, and biochemical techniques (e.g., cell-based assays, reporter gene assays, ELISA, flow cytometry-based assays, qPCR, or imaging, etc.) for immunological and cell-based assay development.
• Experience working with mammalian cell lines and BSL2 level biological agents.
• A strong team player with excellent oral and written communication skills; ability to work independently.
• Strong ability to deliver on complex objectives in a fast-paced, dynamic environment.

Required Skills:

Adaptability, Analytical Method Development, Assay Development, Bioanalytical Analysis, Biochemical Assays, Biological Sciences, Biomedical Sciences, Biopharmaceutical Industry, Biopharmaceuticals, Biopharmaceutics, Cell-Based Assays, Enzyme Linked Immunosorbent Assay (ELISA), Gene Reporter Assays, Immunoassays, Immunochemistry, Innovative Thinking, Mammalian Cell, Microbiology, Strategic Thinking, Technical Writing, Virology