Senior Scientist I, In Vivo (Respiratory Focus) Full-time

Senior Scientist I – Immunology

AbbVie's Immunology R&D organization is expanding its early discovery team to be split between the Cambridge Research Center in Cambridge, MA and the AbbVie Bioresearch Center in Worcester, MA. We are seeking a highly motivated Senior Scientist I to join our expanding immunology team in the area of respiratory diseases. This team is dedicated to building an in vivo group focused on uncovering the underlying mechanisms of airway diseases, paving the way for developing cutting-edge therapeutics.

The ideal candidate will have hands-on experience with in vivo studies with a focus on murine models to investigate immune responses triggered by airway exposure to allergens. We are looking for an enthusiastic, skilled scientist with a passion for bench science and a collaborative mindset. Demonstrated experience working with animal models involving antigen exposure is required. Prior experience assessing lung physiology and working in drug discovery is not mandatory, but is considered highly valuable. Additionally, experience with in vitro respiratory model development is desired. We are seeking an enthusiastic, skilled, and dedicated individual. This position requires passion, attention to detail, prior hands-on experience, and teamwork.

Key Responsibilities:

• Experience with in vivo animal models, especially immunological models
• Design, execute and optimize murine in vivo models of allergen induced airway inflammation and exposure to cigarette smoke. Much of the execution will be done with our animal care team; therefore, excellent communication skills are critical.
• Perform dosing, sample collection (BAL, blood, tissue) and non-terminal procedures in compliance with IACUC.
• Analyze endpoints including cellular differentials, cytokine profiles and lung function.
• Skillful in mammalian cell culture and PCR.
• Hands-on experience with immunoassays including FACS, ELISA, MSD, WB.
• Maintain accurate laboratory records and data.
• Analyze data and present work in internal meetings.
• Work independently and collaboratively across several areas of the company.
• Excellent communication skills.
• Ability to collaborate with peers and their teams.

Qualifications:

• PhD, preferred in Molecular Biology, Immunology or other biological sciences with typically 0-4 years post-doctoral experience; or Master's Degree or equivalent with typically 8+ years of experience; or Bachelor's Degree or equivalent with typically 10+ years of experience.
• Possess thorough theoretical and practical understanding of own scientific discipline.

Key AbbVie Competencies:

• Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance
• Learns fast, grasps the “essence” and can change course quickly when indicated
• Raises the bar and is never satisfied with the status quo
• Creates a learning environment, open to suggestions and experimentation for improvement
• Embraces the ideas of others and nurtures innovation to make possibilities real

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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Pay Range: $94000 – 178500 USD

Role is exclusively performed at a site or office and onsite presence is required. Employees who are site/office-based and can occasionally perform their role virtually work both in the office and remotely*, following the policies and regulations in place at their location. US Employees must be in the office on Tuesday, Wednesday, and Thursday with flexibility to work remotely on Mondays and Fridays. Three days in the office is the minimum; some individuals or teams may require more in-office days due to meetings, business/project needs or their role.