Senior Scientist II, Biologics Purification Full-time

Biologics Purification Scientist

Join AbbVie's Biologics Discovery Sciences group and make a tangible impact in advancing innovative biologic therapies. As a scientist specializing in Biologics Purification, you will play a pivotal role in driving drug discovery, collaborating within a dynamic team dedicated to supporting transformative science that improves patient lives worldwide. Your expertise will help deliver high-purity bispecific antibody-based biologic candidates with suitable purity/characteristics to support the advancement of vital in vitro (i.e. drug-like property assays, binding, cell-based assays, etc.) and in vivo studies (i.e. efficacy, non-GLP NHP PK, DRF, etc.).

Key Responsibilities:

• Lead the purification of bispecific antibody biologics to support critical research assays and studies
• Champion the selection, integration and application of advanced in silico tools to optimize complex protein separation
• Leverage Design of Experiments (DOE) with high throughput automation to evaluate and refine key process parameters to improve protein separation efficiency
• Design and execute advanced chromatography techniques and robust bioprocess development strategies to address production liabilities and enable process scalability.
• Develop automated data capture workflows to enable AI/ML initiatives
• Collaborate with multidisciplinary teams, translating molecular insights into functional results
• Stay current with emerging scientific literature to foster innovation and continuous improvement
• Present findings clearly to diverse audiences and document results with rigor

Qualifications:

• BS, MS, or PhD in Bioinformatics, Biophysics, Chemical Engineering, or related field with typically 12+ years (BS), 10+ years (MS), or 4+ years (PhD) of experience
• Deep proficiency in large-scale bioprocessing, column chromatography, and automated liquid handling platforms
• Proven expertise applying computational tools and predictive modelling to support bioprocess development for bispecific antibodies
• Experience with DOE methodologies and application to multivariate analysis
• Skilled in software systems and/or programming languages, such as Unicorn, Empower, Python/CADET-Process, GoSilico, ASPEN Chromatography, Matlab, JMP, Minitab, Genedata Chromatics, or SDMS platforms
• Experience with data extraction API, ETL tools and LIMS platforms for data acquisition, integration, and management across multiple analytical platforms is a plus
• Strong understanding of molecular and post-translational attributes of biologics
• Exceptional analytical, communication, and presentation skills
• Collaborative spirit and dedication to scientific excellence

Why AbbVie? Here, we combine advanced science with our strong values, cultivating a culture where curiosity is encouraged and meaningful contributions are recognized. Grow your career, innovate boldly, and make a difference in the lives of patients around the globe.

Ready to pioneer the future of biologics? Apply and transform science into health at AbbVie.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.
• This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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Travel: Yes, 5% of the Time

Pay Range: $106500 – 202500 USD

Where We Work

Role is exclusively performed at a site or office and onsite presence is required. Employees who are site/office-based and can occasionally perform their role virtually work both in the office and remotely*, following the policies and regulations in place at their location. US Employees must be in the office on Tuesday, Wednesday, and Thursday with flexibility to work remotely on Mondays and Fridays. Three days in the office is the minimum; some individuals or teams may require more in-office days due to meetings, business/project needs or their role.