Senior Scientist II, Occupational & Environmental Toxicologist Full-time

Toxicologist

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience – and products and services in our Allergan Aesthetics portfolio.

Genetic, Environmental, and Occupational Toxicology (GEO Tox) is a diverse team of scientists with the goals of supporting patient, environmental, and employee safety. The candidate will complete risk assessments supporting occupational, environmental, manufacturing, and regulatory filings. The position will support programs across AbbVie's therapeutic areas and involve a broad range of modalities across all stages from early discovery throughout development to marketed products.

Responsibilities:

• Critically evaluate literature and toxicology reports/summaries and utilize tools such as read-across and in silico data to generate toxicology product risk assessments. This includes toxicology support for extractables and leachables, health-based exposure limits (HBELs) including permitted daily exposure limits (PDEs) and occupational exposure limits (OELs), environmental risk assessments (ERA), and other contaminants.
• Successful collaboration with multi-functional teams to align on safety banding for implementation throughout the company.
• Engage in related external working groups to help drive industry standards and stay informed of upcoming regulations.
• Provide guidance and mentorship to junior team members in GEO Tox and adjacent departments.
• Plan and monitor studies at contract research organizations (CROs) for environmental assessments to support regulatory filings.
• Plan and monitor studies at contract research organizations (CROs) for worker safety studies to occupational safety and handling.
• Support evaluation/implementation of relevant new approach methodologies (NAM)
• Provide technical support for occupational health (hazard) categorizations and chemical registrations, including Globally Harmonized System of Classification and Labelling of Chemicals GHS/CLP, and Safety Data Sheets (SDS).

Qualifications:

• Bachelor's Degree in toxicology or related discipline and typically 12 years of experience OR Master's Degree in toxicology or related discipline and typically 10 years of experience OR PhD in toxicology or related discipline and typically 4 years of experience.
• Previous experience in a pharmaceutical/biopharmaceutical or GMP/GLP industry setting providing risk assessments preferred
• Proven record of successfully evaluating safety risks
• Excellent collaboration, multi-tasking, and communication skills
• Excellent oral and written communication and attention to detail
• Ability to work in a fast-paced environment and meet project deadlines

Desired skills:

• Occupational Exposure Banding, Performance-based exposure control limits, or evaluating toxicity data for Safety Data Sheets
• Risk assessment authoring
• In depth knowledge and experience with regulatory guidance, i.e., ICHQ3C, ICHQ3D, ICHQ3E, ICHM7, ISO-10993-X
• Toxicity data mining in databases and literature
• Broad range of software proficiency as well as in silico predictive tools for toxicity, i.e., QSAR, OECD
• Board-certification preferred but not required

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.