Senior Scientist II/Principal Research Scientist I – Translational Program Science Full-time NEW

Senior Scientist II/Principal Research Scientist I

AbbVie's Local Delivery and Translational Science group seeks a Senior Scientist II/Principal Research Scientist I to lead translational science activities across the eyecare therapeutic portfolio. The successful candidate will drive program execution from preclinical development through early clinical translation in close collaboration with internal teams and external research partners.

Responsibilities

• Serve as translational science lead and primary scientific representative across a diverse, multi-program eyecare development portfolio spanning preclinical through early clinical stages
• Apply computational and data science approaches to synthesize and interpret biological datasets, generating evidence-based insights to support portfolio evaluation and program decision-making
• Oversee preclinical study design, data review, and interpretation in collaboration with internal study teams, ensuring scientific rigor and alignment with program objectives
• Develop translational plans that map preclinical evidence to early clinical decision points, ensuring continuity across development stages
• Coordinate external research partnerships with CROs, academic collaborators, and biotech partners, including data management and scientific communication
• Serve as scientific author for regulatory briefing documents and cross-functional program summaries
• Synthesize input from drug delivery, clinical pharmacology, regulatory affairs, and business development to inform integrated program plans
• Present scientific findings and program-level summaries to internal leadership and at external scientific meetings
• Apply scientific judgment and analytical rigor to evaluate eyecare therapeutic candidates and inform portfolio prioritization and asset advancement decisions

Qualifications

• Senior Scientist II Qualifications: PhD with 4+ years, Master's with 10+ years, or Bachelor's with 12+ years of relevant experience in a biological, biomedical, computational biology, or related life science discipline
• Principal Research Scientist I Qualifications: PhD with 6+ years, Master's with 12+ years, or Bachelor's with 14+ years of relevant experience in a biological, biomedical, computational biology, or related life science discipline
• Therapeutic area experience in ophthalmology, including familiarity with retinal disease biology and multiple treatment modalities
• Proficiency in scientific programming (Python, R, or equivalent) for analysis and visualization of complex biological datasets
• Experience with in vivo preclinical studies, including disease model development, study oversight, and interpretation of pharmacodynamic and efficacy endpoints
• Track record of effective cross-functional collaboration in a matrixed pharmaceutical or biotechnology environment
• Strong scientific communication skills, including preparation of technical documents and presentations to diverse audiences

Preferred Qualifications

• Experience presenting scientific findings to external advisory boards, regulatory bodies, or equivalent forums
• Familiarity with the translational development considerations for novel or emerging ophthalmic therapeutic approaches
• Experience developing or applying translational biomarker strategies in preclinical or early clinical settings

Additional Information

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our long-term incentive programs.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html

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Pay Range: $109500 – 208500 USD

Where We Work

Role is exclusively performed at a site or office and onsite presence is required. Employees who are site/office-based and can occasionally perform their role virtually work both in the office and remotely*, following the policies and regulations in place at their location. US Employees must be in the office on Tuesday, Wednesday, and Thursday with flexibility to work remotely on Mondays and Fridays. Three days in the office is the minimum; some individuals or teams may require more in-office days due to meetings, business/project needs or their role.