Senior Scientist Integrated Bioanalysis – Immunoassay Specialist Full-time

Senior Scientist Integrated Bioanalysis Immunoassay Specialist (Level D)

Location: Multiple locations (Sweden & UK)

Discovery Bioanalysis (DxBA) is a global department within Integrated Bioanalysis, Clinical Pharmacology & Safety Sciences, supporting AstraZeneca's portfolio from early discovery through clinical development. The team applies advanced analytical technologies, including immunoassay, quantitative LC-MS, flow cytometry, multi-omics, and spatial biology to generate high-confidence datasets for decision-making at key project milestones.

Discovery Bioanalysis is responsible for developing and implementing bioanalytical strategies, ensuring robust and reliable data to guide candidate selection and program progression. Working closely with cross-functional project-teams, the group provides comprehensive support across discovery, preclinical, and clinical phases, contributing to the advancement of therapies for complex diseases.

This is an opportunity for a motivated immunoassay expert to join our Integrated Bioanalysis (IBA) team in Cambridge (UK) as a Senior Scientist.

As part of the Discovery Bioanalysis Team, you will develop and validate bespoke immunoassays to assess pharmacokinetics and target engagement biomarkers across diverse therapeutic modalities. The role involves designing, executing, and transferring complex assays using advanced instrumentation to support discovery, preclinical and clinical studies. You will ensure assays are fit for purpose to meet their intended context of use and will collaborate with internal and external partners, reviewing and analyzing data; and troubleshooting assay performance. As a Subject Matter Expert, you will be responsible for enhancing the IBA reputation for scientific excellence by presenting at internal and external meetings, and publishing manuscripts.

Aside from the core laboratory role you will have the opportunity as a Discovery Bioanalytical lead to work within a dynamic cross-functional team in a matrixed environment, defining and executing on tailored & focused project-specific bioanalytical strategies supporting decision-making and advancing the pipeline. You will work in close partnership with key stakeholders across the business, input to project strategy and delivery, managing expectations while interfacing with experienced and highly skilled bioanalytical scientist colleagues or our partnered labs. You will have the opportunity to influence decisions from early discovery through late-stage development and have an immediate and lasting impact to our diverse pipeline.

Essential requirements:

• PhD or MSc (1–3 years' experience), or BSc (3+ years' experience) in immunology, molecular biology, or related field with significant relevant experience.
• Proven expertise as a subject matter expert in ligand-binding immunoassay techniques (expert level for MSD plus one of: Gyrolab, Simoa, SMC-Pro, NULISA, Ella).
• Demonstrated experience in leading bioanalytical project strategy.
• Experience developing robust, state-of-the-art assays for bioanalytical characterization of pharmacokinetics in preclinical and clinical studies, including complex large molecule bioanalysis (e.g., multi-specific antibodies, T cell engagers).
• Expertise in target engagement and occupancy biomarker assay development, including fit-for-purpose approaches.
• Demonstrated experience with total and free assay development to support dose modelling.
• Bioanalytical support for non-GLP IND-enabling studies, including assay qualification and tech transfer for GxP-like and GxP studies.
• Ability to independently design, execute, and troubleshoot assays.
• Proficient in data analysis using Softmax Pro and MSD Workbench.
• Maintain high-quality documentation in electronic lab notebooks and prepare technical reports for regulatory submissions.
• Interpret complex datasets for key project decisions as part of cross-functional, multi-platform teams.
• Effective collaboration in a matrix environment and presentation of findings to scientific and management audiences.
• Agile and adaptable, able to manage multiple projects in a fast-paced setting.
• Strong publication record, communication, and organizational skills; proven accountability and teamwork.

Desirable for the role:

• Experience implementing AI and automation in laboratory and data workflows.
• Experience with ultrasensitive immunoassay platforms (e.g., Simoa, SMC-Pro, NULISA).
• Experience across additional analytical platforms (e.g., spatial, circulatory, molecular technologies such as imaging, cytometry, PCR).
• Background in developing and executing multiplexed immunoassays on Luminex.
• Previous involvement in pharmaceutical research with comprehensive understanding of drug discovery phases and related bioanalytical requirements.
• Basic coding skills for laboratory and data automation.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of four days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Ready to make an impact? Are you ready to make a meaningful and lasting difference? Apply today and join us in our mission to push the boundaries of science and transform medicine. Please submit your application; CV and cover letter, between 15 January 2026 and 28 February 2026.

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.