Senior Scientist, Peptide Synthesis Full-time

Peptide Synthesis Scientist

With global presence, Boehringer Ingelheim has industry-leading expertise in medicine research and development. We are constantly developing the next generation of medical breakthroughs and successfully delivering innovations to meet the medical needs of the patients we serve in the following key areas of interest: cardiovascular, respiratory, metabolic diseases, immunology, oncology and central nervous system. In the future, we will accelerate the launch of more than 10 innovative medicines to meet the demand of Chinese patients.

We are seeking a highly skilled and motivated Peptide Synthesis Scientist to join our team and lead the development of peptide synthesis capabilities from the ground up. The successful candidate will be responsible for designing and executing peptide synthesis workflows using the latest technologies, and will play a critical role in establishing lab infrastructure, protocols, and best practices. Experience in production or scale-up environments is a strong plus.

Key responsibilities include:

• Lead the setup and implementation of peptide synthesis platforms, including equipment selection and method development.
• Design and synthesize peptides using solid-phase peptide synthesis (SPPS) techniques, including Fmoc/t-Boc chemistry.
• Apply cutting-edge technologies and automation tools to improve synthesis efficiency and peptide quality.
• Purify and characterize peptides using HPLC, LC-MS, MALDI-TOF, and other analytical techniques.
• Collaborate with cross-functional teams to support research, development, and production scale-up.
• Troubleshoot synthesis and purification challenges and implement effective solutions.
• Maintain accurate documentation of experiments, protocols, and results.
• Ensure compliance with safety, regulatory, and quality standards.

Qualifications:

• Education and experience required: • Ph.D. or Master's degree in Chemistry, Biochemistry, Pharmaceutical Sciences, or related field. • Minimum 3 years of hands-on experience in peptide synthesis, preferably including lab setup or platform development. • Familiarity with advanced peptide synthesis technologies and automation systems. • Experience in production or scale-up environments is highly desirable.
• Knowledge and skills: • Strong expertise in SPPS and peptide purification/characterization. • Knowledge of peptide modifications (e.g., cyclization, PEGylation, labeling) is a plus. • Excellent problem-solving and analytical skills. • Strong communication and collaboration abilities. • Ability to work independently and manage multiple projects.
• Additional information: • Competitive compensation and benefits package. • Opportunity to build and shape a new peptide synthesis capability. • Innovative and collaborative work environment.