Senior Scientist, TCR Therapy Full-time

Senior Scientist, TCR Therapy

Gaithersburg, US | full time | Job ID: 11079

About the Role

Join our pioneering team in Gaithersburg, MD, as a Senior Scientist dedicated to advancing personalized TCR therapies targeting patient-specific cancer antigens for solid tumors. In this impactful role, you will lead cutting-edge scientific initiatives to refine our TCR platform and translate it into scalable clinical therapies, directly contributing to BioNTech's mission of transforming patient outcomes through innovative immunotherapy solutions.

You will thrive in a collaborative and dynamic environment that values scientific rigor and innovation. As part of a global network of experts, your contributions will shape the future of personalized therapies and make a meaningful difference in patients' lives.

Your Contribution

Design and execute studies to enhance our TCR platform, focusing on multiplexed TCR delivery meeting safety, efficacy, and scalability standards. Establish, optimize, and troubleshoot high-throughput workflows supporting discovery, screening, and validation activities. Drive innovation by adopting novel technologies and methodologies aligned with evolving scientific and clinical needs. Lead cross-site and cross-functional collaborations to ensure timely delivery of project milestones. Mentor team members while fostering a high-performance culture and professional development. Communicate findings effectively through tailored presentations for executive and technical audiences.

A Good Match

PhD in Immunology, Biomedical Sciences, or related field with deep expertise in tumor immunology or TCR/neoantigen biology. Proficiency in immunological techniques such as T cell functional assays, FACS analysis, IncuCyte assays, and cell line engineering. Advanced computational skills (Python/R) with knowledge of AI/ML applications in immunology or experience collaborating with AI/ML teams. Strong organizational skills with meticulous experimental documentation. Proven ability to excel in fast-paced environments while adapting to evolving priorities.

Preferred requirements: experience with personalized immunotherapies or spatial biology approaches like spatial transcriptomics.

US based candidates expected. Pay Range: $113,600 – $181,600/year + benefits, annual bonus & equity (bonus and equity is variable and dependent on company and individual performance). Compensation for the role will depend on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities.

Your Benefits

BioNTech US is committed to employee wellbeing and offers best-in-class benefits & HR programs to support an inclusive & diverse workforce. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:

• Medical, Dental and Vision Insurance
• Life, AD&D, Critical Illness Insurance
• Pre-tax HSA & FSA, DCRA Spending Accounts
• Employee Assistance & Concierge Program (EAP) available 24/7
• Parental and Childbirth Leave & Family Planning Assistance
• Sitterstream: Virtual Tutoring & Childcare Membership
• Paid Time Off: Vacation, Sick, Bereavement, Holidays (including Floating) & Year-End U.S. Shutdown.
• 401(K) Plan with Company Match
• Tuition Reimbursement & Student Loan Assistance Programs
• Wellbeing Incentive Platforms & Incentives
• Professional Development Programs
• Commuting Allowance and subsidized parking
• Discounted Home, Auto & Pet Insurance

…and more! More details to be shared.

Located in the BioHealth Capital Region near Washington DC and ranked among the top biopharma hubs in the country, Gaithersburg, Maryland offers a unique and diverse cluster across industry, government, and academia for top talent and scientific innovation. As a pivotal player within the life sciences community, Gaithersburg is distinguished by its robust infrastructure and strategic location near the nation's capital. The city's strategic significance is amplified by its state-of-the-art manufacturing facilities that cater to the rigorous demands of the life sciences industry; Gaithersburg's manufacturing sector is defined by advanced technologies and complies with the most stringent regulatory standards, ensuring the production of high-quality pharmaceuticals, biologics, and medical devices. In the coming years, Gaithersburg will continue to be a vital contributor to the future of medical science and technology.

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BioNTech, the story

At BioNTech, we are more than just a biotechnology company – we are a community of innovators, scientists, and leaders dedicated to revolutionizing medicine by translating cutting-edge science into survival. Your contributions here have the potential to improve the health of people worldwide, especially by addressing diseases with high medical needs like cancer and various infectious diseases.

Experience a dynamic workplace that embraces diversity in all its forms. We foster innovation, encourage creativity, and develop business strategies driven by our shared passion for advancing medicine.

Working at BioNTech means striving to achieve medical breakthroughs while growing your career in a meaningful way. Apply today and become part of a mission that has the potential to change lives around the world.

BioNTech does not tolerate discrimination, favoritism or harassment based on gender, political views, religion or belief, nationality, ethnic or social origin, age, sexual orientation, marital status, disability, physical appearance, health status or any other physical or personal characteristics. BioNTech is committed to creating a diverse and inclusive work environment. We are proud to be an equal opportunity employer. The main thing is that you suit us, and we suit you!

BioNTech – As unique as you

www.biontech.com

Nearest Major Market: Washington DC