Senior Scientist, Translational Research Full-time NEW

Senior Scientist Oncology Translational Research

Working with Us Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

The Oncology Thematic Research Center at BMS is a key research and early development engine, responsible for the discovery and development of novel oncology therapeutics for patients. Centered at our state-of-the-art research sites in Cambridge and Seattle, scientists focus on novel targets and pathways for tumors that are refractory to current therapies. With a deep understanding of the causal human biology, we are able to leverage our multiple modality platforms to best match the modality to the mechanism and desired outcome. We are a fully integrated drug discovery through translational and early clinical development organization which exploits state-of-the-art in vitro, in vivo and ex-vivo models of Cancer biology and Immuno-oncology to identify and validate targets. We partner closely with colleagues in Translational Medicine, Informatics and Predictive Sciences and Early Clinical Development to generate biomarker and patient enrichment hypotheses to enable efficient decision making in early clinical trials. We are optimally positioned to complement the world-class translational expertise, biology and leading academic research centers in the area.

Our Bristol Myers Squibb research site in Cambridge Crossing will help us continue to deliver on our mission, positioning the company and our scientists in the heart of a vibrant ecosystem of world-class science, innovation, and business opportunities.

Position Summary

We are seeking an experienced individual with oncology research expertise to join the Translational Research team within the Oncology Thematic Research Center at Bristol Myers Squibb in Cambridge, MA. The qualified candidate is a highly motivated, engaged, and creative scientist that can thrive in a highly matrixed organization to advance programs from candidate optimization through IND enabling activities and ultimately to Proof-of-Concept clinical trials. This individual will play a pivotal role in shaping and driving translational strategies for oncology assets, enabling the development of transformative cancer therapies for patients.

Position Responsibilities

In the role as a Senior Scientist within Oncology Translational Research, the ideal candidate:

• Design and develop biomarker, pharmacodynamic, and target engagement assays to understand drug mechanism of action and response.
• Perform laboratory-based experiments and data analysis to support clinical oncology studies, using various in vitro oncology and cancer immunology models and assays.
• Interact with project teams and contract laboratories for the design, execution, and oversight of molecular, cellular, and/or in vivo studies.
• Collaborate with cross-functional teams and external partners (CROs, specialty labs) to generate high-quality biomarker data for clinical studies.
• Contribute to translational plans, sample collection strategies, and documentation for early-phase trials.
• Present experimental results and share scientific insights with project teams and stakeholders.
• Proactively provides insight into novel ways to incorporate biomarkers into clinical designs to enable early understanding of emerging drug profiles, as well as input around tumor types and potential impact of biomarkers on internal decision making.
• Provides oversight to progress validated biomarkers into development of diagnostic assays, as needed
• Participates in strategic review and input to presentations, publications and internal/external communications along with accountable program leadership and in governance forums
• Develops solutions and courses of action for senior staff, including identification of risks and risk mitigations
• Shares expertise, experience, lessons learned and knowledge with translational and other relevant scientific experts and colleagues across the organization

Experience

Basic Qualifications:

• Bachelor's Degree with 7+ years of academic and/or industry experience
• Or Master's Degree with 5+ years of academic and/or industry experience
• Or Ph.D. or equivalent advanced degree in the Life Sciences with 2+ years of academic and/or industry experience

Preferred Qualifications:

• PhD or MD/PhD with 2+ years of relevant industry experience in the drug development process, preferred within oncology translational biomarker roles and with solid tumor and immune oncology experience.
• Strong scientific acumen and mechanistic understanding of disease biology, with experience contributing to oncology and immuno-oncology drug development.
• Hands-on experience designing, executing, and analyzing translational biomarker assays and data across multiple technologies (e.g., genomics, immunohistochemistry, flow cytometry, immunoassays) and sample types in clinical studies.
• Familiarity with the drug development process and experience collaborating with clinical teams; able to communicate results and contribute to discussions in cross-functional settings.
• Demonstrated ability to work effectively with internal stakeholders and external partners (e.g., CROs, specialty labs).
• Excellent communication, organizational, and teamwork skills, with a proactive and collaborative mindset.
• Eagerness to learn, grow, and take on increasing responsibility in a fast-paced environment.

Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients' lives through science™ “, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodations/adjustments prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

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