Flatiron Research Fellow, Biophysical Modeling, Center for Computational Biology
Flatiron Institute – Simons Foundation
Location
162 5th Avenue, NY, NY 10010
Open Date
Sep 16, 2025
The https://www.simonsfoundation.org/flatiron/center-for-computational-biology/ (CCB) of the https://www.simonsfoundation.org/’s https://www.simonsfoundation.org/flatiron is actively seeking enthusiastic, full-time post-doctoral Flatiron Research Fellows to join its
https://www.simonsfoundation.org/flatiron/center-for-computational-biology/biophysical-modeling/ in 2026.
The goal at CCB is to advance the understanding of fundamental and historically challenging biological processes by developing theory, innovative modeling tools for large-scale biophysical simulations, and computational frameworks for analyzing increasingly large and complex experimental datasets. Living systems are built hierarchically; as such, CCB’s research activities span several scales of biological organization, bridging the gap between microscopic detail and large-scale behaviors, and providing natural continuity between our groups’ efforts. CCB currently comprises more than 45 research and data scientists at career stages from recent Ph.D. graduates through senior scientists, as well as visiting scientists, guest researchers, graduate students, interns, and administrative support staff. For a full description of CCB research areas and scientific staff, please see https://www.simonsfoundation.org/flatiron/center-for-computational-biology/.
The Biophysical Modeling group focuses on the modeling and simulation of complex systems that arise in biology and soft condensed matter physics. Areas of interest include the dynamics of complex and active materials, and aspects of collective behavior and self-organization in both natural systems (e.g., inside the cell) and synthetic ones. Ongoing projects focus on understanding the organization and dynamics of the nucleus, the structure and assembly of spindles, the positioning and transport of cellular organelles, and fluid-structure problems in biology. To address these, often in close collaboration with experimental collaborators, we build numerical and theoretical models from the ground up, revealing how the known mechanics of individual components give rise to collective behavior. Many such phenomena occur only within dense, highly interacting systems, inaccessible to standard techniques. To probe such regimes requires the development of fast and scalable algorithms for many-component systems, and of coarse-grained models that can be analyzed and simulated.
Strong applicants with backgrounds in applied and computational mathematics, biophysics, engineering, statistical inference, and related fields are particularly encouraged to apply.
POSITION DESCRIPTION
Flatiron Research Fellows in CCB are individuals at the postdoctoral level with backgrounds in one or more of the following areas: applied mathematics, statistics, computational biology, biophysics, computer science, engineering, mathematical physics, or related disciplines.
Fellows are expected to carry out an active research program that can be independently directed and/or involve substantial collaboration with other members of CCB or the Flatiron Institute. In addition to their research, Fellows help build the rich scientific community at CCB and the Flatiron Institute by participating in seminars, colloquia, and group meetings; developing their software, mathematical and computational expertise through internal education opportunities; and sharing their knowledge through scientific publications, presentations, and/or software releases, with the financial support of the Institute. Fellows have access to the Flatiron Institute’s powerful https://www.simonsfoundation.org/2021/03/04/computation-opens-new-doors-for-science/.
Responsibilities include but are not limited to:
FRF positions are generally two-year appointments that can be renewed for a third year, contingent on performance. Fellows will be based, and have a principal office or workspace, at the Simons Foundation’s offices in New York City. Fellows may also be eligible for subsidized housing within walking distance of the Flatiron Institute.
For more information about careers at the Flatiron Institute, please click https://www.simonsfoundation.org/flatiron/careers.
Qualifications
Education
Related Skills & Other Requirements
Compensation and Benefits
Application Instructions
To apply, please submit the following via the application portal:
Applications for available positions that begin in 2026 will generally be reviewed beginning November 2025, and will be considered on a rolling basis until the positions are filled. For full consideration, candidates are strongly encouraged to submit their complete application by November 15, 2025.
SELECTION CRITERIA
Applications will be evaluated based on:
Any queries about the application process or about CCB should be directed to mailto:ccbjobs@flatironinstitute.org. Queries about CCB may also be directed to scientific staff at CCB.
Our Commitment to Expanding Pathways to Science & Opportunities for All:
Many of the greatest ideas and discoveries come from a diverse mix of minds, backgrounds, and experiences. The Simons Foundation is committed to advancing basic science and mathematics to benefit humankind and expand our collective understanding of our world. As part of our mission, we support partners, programs, and initiatives that seek to broaden the scientific community and open pathways to science and mathematics careers.
The Simons Foundation provides equal opportunities to all applicants without regard to race, religion, color, age, sex, pregnancy, national origin, sexual orientation, gender identity, genetic disposition, neurodiversity, disability, veteran status, or any other protected category under federal, state, and local law.
To apply, please visit: [Please click the Apply button for the link or address]
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