Sr. Scientist I, Brain Transport Biology Full-time

Discovery Neuroscience In Vivo Pharmacology Scientist

The Discovery Neuroscience In Vivo Pharmacology group in Cambridge, Massachusetts, is seeking a highly skilled and self-motivated scientist to join a dynamic team supporting target identification, validation, and drug transport facilitation over brain barriers. The ideal candidate will have strong hands on experience with various ex vivo analysis techniques including biochemistry and qPCR.

Key Responsibilities:

• Responsible for design and implementation of ex vivo analysis of tissue samples from in vivo studies testing multispecific biologics, small molecules, and siRNAs to support projects in the areas of Alzheimer's and Parkinson's disease
• Identify and solve technical problems independently, implement new assays and workflows, conceive and implement innovative research ideas
• Ensure consistency and quality of technical reports
• Present original work internally across departments

Minimum Qualifications:

• Bachelor's Degree or equivalent education and typically, 10 years of experience, Master's Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary.
• Experience with ex vivo readouts including biochemistry (ELISA, WB), qPCR and immunohistochemistry
• Proven track record of working in multidisciplinary in vivo pharmacology teams
• Experience with in vivo models of neurodegeneration, particularly with models of Alzheimer's and Parkinson's Disease
• Proven track record in characterizing complex biotherapeutics in vivo (biologics, small molecules, siRNA)
• Excellent organizational skills and the ability to manage multiple studies simultaneously
• Candidate must be a goal-oriented team player with excellent verbal and written communication skills and strong “can-do” attitude

Preferred Qualifications:

• Experience with digital PCR and MSD assays
• Experience with image analysis

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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