Staff Scientist – Nephrology Full-time

Job Title

The Mahjoub laboratory studies the role of the cell cytoskeleton in regulating cell physiology, tissue formation, and organ development, with specific focus on microtubule-based organelles called centrosomes and cilia. Our aim is to determine the consequences of centrosome-cilia defects in the development of human ciliopathy syndromes, with specific focus on renal and pulmonary ciliopathies. This specific project involves characterization of centrosome defects and how they cause cystic kidney disease. The experiments involve multiple systems and tools including primary cell cultures and organoids, transgenic mice, advanced microscopy techniques (Superresolution, ultrastructure expansion, electron, and live-cell imaging), as well as standard molecular and biochemical laboratory methods. Designs research protocols. Assists in developing and conducting research projects, including experiment design, data analysis and documentation of experiment results.

Primary Duties & Responsibilities:

• Following instructions and discussions with the principal investigator, designs research protocols, including developing procedures for the collection, verification and management of data.
• Assists with grant preparation and reporting.
• Performs complex statistical analysis of data collected and writes interpretative reports. Verifies the correctness of the data submitted and makes recommendations based on these analyses.
• Documents research topics and prepares and submits papers based on research work to publications and committees for publication or presentation to peers.
• Solves practical problems relating to difficulties with equipment or test subjects. Suggests technical or procedural improvements in testing methods.
• Conducts literature searches related to research project.
• Performs other duties as assigned.

Working Conditions:

• Works in a laboratory environment with potential exposure to biological and chemical hazards.
• Must be physically able to wear protective equipment and to provide standard care to research animals.

The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Required Qualifications:

Education: Master's degree or combination of education and/or experience may substitute for minimum education.

Certifications/Professional Licenses: No specific certification/professional license is required for this position.

Work Experience: Laboratory Operations (3 Years)

Skills: Not Applicable

Driver's License: A driver's license is not required for this position.

More About This Job:

Preferred Qualifications:

• Extensive experience using preclinical mouse models of human disease. This includes handling mice, genotyping/phenotyping, drug administrations in mice, etc.
• Isolation of organs, tissues and other samples from mice, and analysis by these specimens by histology and other methods.
• Prior training in mammalian cell culture and/or organoid systems.
• Experience with immunofluorescence microscopy.

Preferred Qualifications:

Education: Ph.D. – Doctor of Philosophy

Certifications/Professional Licenses: No additional certification/professional licenses unless stated elsewhere in the job posting.

Work Experience: No additional work experience unless stated elsewhere in the job posting.

Skills: Analytical Problem Solving, Communication, Computer Literacy, Data Analysis, Data Interpretations

Salary Range:

$48,000.00 – $86,900.00 / AnnuallyThe salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.

Benefits Statement:

Personal: Up to 22 days of vacation, 10 recognized holidays, and sick time. Competitive health insurance packages with priority appointments and lower copays/coinsurance. Take advantage of our free Metro transit U-Pass for eligible employees. WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.

Wellness: Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!

Family: We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We've got you covered. WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.

EEO Statement:

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the University's policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.Washington University is dedicated to building a community of individuals who are committed to contributing to an inclusive environment – fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.