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Postdoctoral Fellow
PostDoctoral Associate in Disease Modeling Full-time
Job Summary:
The Walczak Lab at the University of Colorado is seeking a highly motivated and creative Postdoctoral Researcher to join our multidisciplinary team focused on the molecular mechanisms of neurodegeneration. Our research integrates chemical biology, protein biochemistry, and stem cell-based models to uncover how pathogenic proteins contribute to diseases such as Alzheimer’s and frontotemporal dementia. The successful candidate will lead a project involving human iPSC-derived models to study proteinopathies, including tau and other proteins implicated in neurodegenerative diseases. The position will involve differentiation of stem cells into neuronal and glial subtypes, gene editing, advanced imaging, and proteomics to investigate protein aggregation, post-translational modifications, and cellular phenotypes linked to disease.
CU is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.
Who We Are:
As one of the nation’s top-ranked Tier 1 research institutions, the Department of Chemistry is internationally recognized for its outstanding research efforts and education. The Chemistry faculty conduct research in all areas of chemistry, including analytical, materials and nanoscience, organic, and physical chemistry. The Department of Chemistry is a part of the College of Arts and Sciences at the University of Colorado Boulder, whose faculty conduct research, scholarship, creative work, and education in more than 60 fields. The college leads nationally in undergraduate and graduate education, bringing world-class research and scholarship to our students, both in and out of the classroom. The college is the academic home to all five of the university’s Nobel laureates. Additionally, it is home to the university’s four National Medal of Science winners, eight MacArthur “Genius Award” winners, 100 Fulbright Scholars, 17 Guggenheim Fellows, 14 Packard Fellows, 24 members of the National Academy of Sciences, and 23 members of the American Academy of Arts and Sciences. CU-Boulder is the only university in the Rocky Mountain region in the American Association of Universities, a group of the nation’s leading research institutions.
Key Responsibilities:
– Culture and differentiate human iPSCs into neuronal and glial lineages
– Perform molecular and biochemical characterization of protein aggregation and clearance
– Utilize gene editing to generate disease-relevant models
– Collaborate with biophysicists, chemists, and neuroscientists within and outside the lab
– Prepare manuscripts and present findings at scientific conferences
What We Require:
– Ph.D. in Cell Biology, Neuroscience, Molecular Biology, or a related field
– Excellent communication, teamwork, and problem-solving skills
What We Would Like to Have:
– Experience with stem cell or mammalian cell cultures
– Familiarity with neurodegenerative disease models and protein aggregation mechanisms preferred
Special Instructions:
To apply, please submit the following materials:
- Resume or CV
- Cover letter addressed to the Search Committee briefly describing your qualifications, professional goals, and specific interest in this position.
If you are selected as the finalist, your degree will be verified by the CU Boulder Campus Human Resources department using an approved online vendor. If your degree was obtained outside of the United States, please submit a translated version as an optional attachment.
During the application process, you will need to enter the contact information for two references. We will request letters of recommendation and additional materials, if needed, as the search progresses.
For full consideration, please apply by June 30, 2025. This position will remain open until either this requisition or requisition #64470 is filled.
Note: Application materials will not be accepted via email. For consideration, applications must be submitted through CU Boulder Jobs.
In compliance with the Colorado Job Application Fairness Act, in any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.