2D and 3D cell culture systemsadvanced statistical analysis using R and PythonAnalytical Method Development/ValidationBioinformaticsChemical ProteomicsComputational BiologyDe Novo proteomicsHeavy experiences in MS-based protein interactome analysisin vitro molecular and cellular assaysMass Spectrometryoncology researchPhosphoproteomicsProtein DesignTargeted Protein DegradationTranslational oncology
Co-developed InstaNovo-P a de novo search algorithm for phosphoproteomics, responsible for the phosphoproteomic validation of the identified targets. Experimental design of in vitro validation.
Contribution to Project (2)
Developed the isoform elucidation of FGFRs in breast cancer cells using targeted proteomics and computational biology.
Contribution to Project (3)
Elucidated the role of dermokine in keratinocytes using computational biology, proteomics, phosphoproteomics, degradomics and cellular assays. Further used cloning strategies to validate phosphomutants.