Assoc Prin. Scientist, Analytical R&D Full-time

Pharmaceutical Materials Scientist

The Materials & Biophysical Characterization (MBC) group within Pharmaceutical Analysis & Digital Technologies is seeking a highly motivated and technically focused individual interested in positively impacting our Company's pipeline from discovery through development and commercial launch.

This position is for a Pharmaceutical Materials Scientist to be a key member of a team responsible for the physicochemical characterization of pharmaceutical materials including small molecule active pharmaceutical ingredients (API), chemical intermediates, peptides, novel excipients, drug-product intermediates, and drug products.

The candidate will utilize their expertise in physical organic chemistry or materials science as a member of cross-functional teams to tackle scientific challenges related to crystallization, polymorph and salt-selection, drug-excipient compatibility, characterization of amorphous solid dispersions, and physical stability API and drug products. Additional expectations include building a strong network internally and across the external academic and regulatory community. Furthermore, the selected candidate will advance a culture of scientific excellence, a compliance mindset, and collaboration with partners and stakeholders across our Company's network such as Discovery Chemistry, Process & Analytical Chemistry, Chemical Engineering and Formulations Sciences.

Education Requirements

• Bachelors or Masters degree in Materials Science and Engineering, Chemistry, Chemical Engineering, Pharmaceutical Sciences or related discipline, with a minimum of eight (8) years relevant industrial experience (non-academic). OR
• PhD in Materials Science and Engineering, Chemistry, Chemical Engineering, Pharmaceutical Sciences or related discipline with 4 years relevant industrial experience (non-academic).

Experience and Skills

Required

• Expertise in materials science or physical chemistry with experience in materials characterization techniques such as X-ray diffraction, thermal analysis, electron microscopy, vibrational spectroscopy, particle size analysis or powder property characterization.
• Strong academic record including publications in peer reviewed journals and presentations at scientific meetings
• Self-motivated, creative and energetic scientist willing to continually learn and solve complex problems.
• Strong written and verbal communications

Preferred

• Active pharmaceutical ingredient (API) polymorph screening and crystallization.
• Amorphous solid dispersion characterization
• Modified release dosage forms
• Automation and data science
• Late-stage product development and regulatory documentation / filing.

Required Skills: Analytical Chemistry, Analytical Method Development, Assay Development, Biological Assay Development, Cell-Based Assays, Chemical Engineering, Chromatographic Techniques, Crystallizations, High Resolution Mass Spectrometry (HRMS), Liquid Chromatography-Mass Spectrometry (LC-MS), Mass Spectrometry Analysis, Pharmaceutical Sciences, Process Analytical Technology (PAT), Protein Analysis

Preferred Skills:

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As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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The salary range for this role is $142,400.00 – $224,100.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.