Associate Principal Scientist – Process Analytical Technology (PAT) and Chemometrics Full-time

Associate Principal Scientist

As an Associate Principal Scientist, you will provide expert support to continuous manufacturing of commercial products. Your knowledge in PAT, analytical science and technologies will be crucial in ensuring efficient and effective support to internal and external manufacturing sites and testing laboratories located in multiple countries.

Essential Skills/Experience:

• Ph.D. – 5+ years, MS – 8+ years, BS – 10+ years of relevant industry experience. Degree in relevant field (Analytical Chemistry, Pharmaceutical Sciences, or Engineering etc.)
• Data Analytics, including Chemometrics, Multivariate Data Analysis (MVDA) and Machine Learning with demonstrated success in the development and validation of multivariate methods in a commercial environment.
• Expertise in PAT (e.g.: spectroscopic) methods used in association with chemometric models in commercial setting and PAT orchestration (e.g. SIPAT/SynTQ).
• Expertise in PAT interface with commercial processes (in-line, on-line, at-line) and control strategy.
• Expertise defining business strategy for the integration of PAT/MSPC in the on-market space.
• Scientific leadership skills
• Understanding of Technology Transfer in the Pharmaceutical industry
• Proven track record to think and operate across functional boundaries
• Effective influencing and prioritization skills
• Good communication and stakeholder management skills
• A strong understanding of key process analytical technologies, especially NIR, Raman and microwave resonance spectroscopy
• Demonstrated expertise in PAT method development, implementation, optimization and use of Multi-variate data analysis/ Chemometrics (MVDA, PCA, PLS)
• Experience with chemometric modelling software such as SIMCA, Unscrambler, MATLAB, or similar tools for developing, validating, and maintaining multivariate models in a commercial environment.
• Knowledge of the principles and management of Safety, Health & Environment (SHE)
• Business acumen and capability to understand business cases in subject matter areas.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.