Associate Scientist – Neuroprotection and Resilience Full-time

Associate Scientist – Neuroprotection and Resilience

Location: Cambridge, MA

We are looking for a highly qualified and motivated Associate Scientist to join the neuroprotection and resilience cluster in the Neurology Therapeutic Area for a one-year fixed contract, focused on discovering, validating, and developing therapies for neurodegenerative diseases including Alzheimer's, Parkinson's, and ALS. This position is laboratory-based and will involve executing in vitro and in vivo experiments to identify and test new therapeutics. The successful candidate will have experience working in neurodegeneration in an academic or industry setting, with experience to perform cell culture-based experiments using iPSC cells and/or cell lines and supporting animal studies in models of brain disease. The ideal candidate will also have experience running different biochemical/bioanalysis assays including ELISA based systems.

Join the engine of Sanofi's mission — where deep immunoscience meets bold, AI-powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions.

We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.

Main Responsibilities:

• Establish and maintain human iPSC-based cell cultures (2D and 3D), including monocultures and tricultures, to support compound and antibody screening activities, modeling disease-relevant and neuroinflammatory mechanisms in the CNS.
• Measure compound exposure from mouse and NHP tissues and assess pathway modulation using biochemical and molecular assays including ELISA, Western blotting, and related methodologies.
• Support in vivo studies aimed at evaluating compound pharmacokinetics (PK) and pharmacodynamics (PD) across multiple routes of administration, including intraperitoneal (IP), oral (PO), and intravenous (IV) delivery.
• Design and execute experiments with scientific rigor; analyze and interpret data; and clearly communicate findings through internal and external presentations, reports, and team discussions.
• Develop new lab workflows, integrating automation and AI where possible.
• Collaborate effectively within a highly matrixed, cross-functional research environment across the Neuro Therapeutic Area and enabling research platforms.
• Contribute to the advancement of novel drug candidates from early exploratory discovery through preclinical development and transition toward clinical stages.

About You

Basic Qualifications

• Education: Bachelor's degree in Life Sciences or related scientific discipline
• Experience: Minimum 1 year of relevant laboratory experience in academic, research or biopharmaceutical setting
• Experience with in vitro models and tools
• Ability to maintain good laboratory research practice from lab execution to record keeping

Preferred Qualifications

• Animal Research: Experience working with rodent models and proficiency in tissue collection and dosing
• Advanced Lab Skills: Experience with in vitro models and tools beyond basic requirements
• Good organizational and communication skills
• Willingness to work both independently as well as on a team
• Interest and enthusiasm to actively participate in daily group and laboratory functions.

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.
• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.