Associate Scientist, Novel Oligonucleotide Delivery Platforms Full-time

Associate Scientist

We are seeking a highly motivated associate scientist to join the Non-Viral Delivery Technologies group within Regeneron Genetic Medicines. You will support production, purification, and characterization of proteins and larger macromolecular protein-based nanocarriers to be used in next-generation delivery technology development, further expanding the company's growing genetic medicines portfolio.

In this role, a typical day might include the following:

• Maintenance and manipulation of bacterial and mammalian cells for protein expression
• Designing and cloning constructs into appropriate expression vectors
• Operation of AKTA systems for small scale purification by liquid chromatography-based techniques (e.g. affinity, ion exchange, size exclusion)
• In vitro reporter assays with adherent and suspension cell lines or primary cells
• Characterization of proteins (e.g. SDS-PAGE, SE-UPLC, CE, DLS)
• Working collaboratively with other team members and groups around the company

This role might be for you if you:

• Enjoy working in a fast-paced environment with rapid hypothesis generation and testing
• Can troubleshoot through logistical and technical hurdles as they arise
• Can work independently and show initiative to continually improve protocols and processes
• Can tolerate failure, ambiguity, data-driven pivots on changing priorities and project direction

To be considered for this role, you must have:

• A BS/MS in molecular biology, biochemistry, bioengineering, or related field
• Previous experience in cloning, bacterial-based expression systems, self-assembled VLPs are a plus.
• Experience with aseptic technique used in mammalian cell culture, chromatography, running an AKTA Pure, and SDS-PAGE/CE are distinct advantages.
• To be successful in this role, you need to work collaboratively, have attention to detail, and be organized.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.