Biologics Process Research & Development, Associate Scientist Full-time NEW

Associate Scientist In Biologics' Process Development

Biologics Process Research & Development (BPR&D) within our company's research laboratories is on a mission to rapidly deliver biotherapeutics to patients by efficiently developing innovative, robust manufacturing processes and technologies. To achieve this, we work closely with colleagues in discovery, pre-clinical, early development, analytical, formulation, and commercial manufacturing while providing an inclusive environment for all. Beyond process development for pipeline biologics, we innovate and build next generation biomanufacturing technologies. Examples include investments for development of continuous manufacturing, green and sustainable processes, and proprietary technology platforms. We actively publish and engage with the scientific community to influence the field.

Biologics Process Research & Development (BPR&D) includes three lab-facing technical functional areas: process cell sciences (PCS), upstream and downstream process development & engineering. The latter two together form our biologics' process development (BPD) group. This job posting covers opportunities for the BPD group. We are actively looking for highly motivated people with a passion for innovation and interest in contributing to upstream and/or downstream bioprocessing.

As an associate scientist in biologics' process development (BPD) you will work with a highly collaborative team of scientists and engineers to design, develop and execute robust processes in support of early- to late-stage biological products. You will apply rigorous scientific principles to solve challenging problems focused on developing the best processes to deliver life-changing medicines to patients worldwide. You will also have an opportunity to contribute to additional areas of interest such as biophysical, process, economic and/or multivariate modeling as we are committed to leveraging digital ways of working to enhance our ability to design robust processes.

Responsibilities include but are not limited to:

• Contribute to the development of innovative and disruptive technologies for next-generation biologic manufacturing processes
• Develop and characterize robust clinical processes capable of delivering multi-kilogram quantities of drug substance
• Independently design and conduct experiments for individual unit operations using relevant operational parameters and analytical inputs
• Integrate unit operations both physically and with relevant process control and monitoring platforms for concurrent operations
• Collaborate across the department, process analytics, and other functional teams in both research & development and manufacturing to advance the biologics pipeline
• Conduct laboratory-scale and/or pilot-scale studies to support scale-up and tech transfer of processes
• Contribute to a safe and compliant laboratory work environment

Minimum education requirements:

Education: BS (or expected completion within 6 months of application) in chemical/biochemical/biomedical engineering, biotechnology, biochemistry, microbiology, structural biology, or related fields

Required experience and skills:

Scientific understanding of the engineering principles for recombinant protein production unit operations.

Knowledge with aseptic technique, protein biophysical properties, and general protein laboratory practices

Strong passion and commitment to integrate science and innovation into biologics' process development

Preferred experience and skills:

Experience with molecular biology, protein expression, mammalian cell culture, protein purification, biochemical engineering, or protein analytical technologies

Knowledge of statistical data analysis tools such as the design of experiments and multivariate data analysis