Doctoral Researcher in Cell Biology, Centre of Excellence in Immune – Endothelial Interfaces Full-time

Doctoral Researcher in Cell Biology, Centre of Excellence in Immune – Endothelial Interfaces

The newly established Finnish Centre of Excellence in Immune – Endothelial Interfaces (IMMENs) invites applications for a fixed-term (2-years) position of a Doctoral Researcher. The successful candidate will work in the research group of Dr. Kari Vaahtomeri at the Faculty of Medicine, University of Helsinki. Scientific context IMMENs, composed of research groups at the University of Helsinki and Åbo Akademi in Turku, investigates the role of lymphatic vessel endothelium in controlling immune responses. Current evidence shows that much of immune regulation occurs locally at the site of inflammation. Recent studies have revealed important crosstalk between lymphatic endothelium and immune cells, resulting in phenotypic changes that control immune cell trafficking, fate and function. IMMENs will develop novel experimental approaches to uncover the mechanisms and therapeutic potential of lymphatic endothelial immunomodulation in homeostasis, inflammation and tumorigenesis using in vivo genetic mouse models, advanced live and intravital imaging, engineered microchip models, primary cell co-culture systems and novel microscopy and analysis methods. In this context, Vaahtomeri laboratory addresses fundamental cell biology mechanisms of cell migration/interactions.

We are looking for candidates with a strong background in life sciences (for example, cell biology, biochemistry or mouse models). The candidate should be highly motivated to investigate key open questions in the fields of: Cell Biology Vascular biology Immunology At the pre-doctoral level, previous experience in cell biology, vascular biology, mouse models, immunology or high-end imaging approaches is considered an advantage. Doctoral Researcher must obtain the right to pursue doctoral studies at the University of Helsinki within the trial period of six months. Candidates should be able to demonstrate abstract thinking as well as the potential to develop and pursue scientific projects in the fields relevant for this call. Furthermore, the candidate should have excellent communication skills in English and the ability to work in an international environment.

The initial appointment is for 2 years and includes a possibility for extension upon success in doctoral research. The position will be filled immediately upon identification of suitable candidates. The starting date is negotiable. Salary will be commensurate with qualifications and experience based on the University of Helsinki guidelines. The chosen applicant is expected to reside in Finland while employed by the University of Helsinki. The work is supervised by Dr. Kari Vaahtomeri and takes place in the context of the active research community of IMMENs groups. The research group has prominent international connections and is located at the medical campuses in the University of Helsinki. The immediate research environment provides state-of-the-art facilities, cutting-edge expertise in vascular-, tumor-, immunological- and stem cell biology, and great synergy with renowned research groups.