A Postdoctoral position is available for a determined, people-smart, and driven basic scientist to join the laboratory of Vascularized Composite Allotransplantation (VCA) at Johns Hopkins University School of Medicine. The VCA Lab is a multi-disciplinary research laboratory standing on the pillars of transplant immunology and immunoregulation, regenerative medicine, tissue cryopreservation, and nerve research. We look for dynamic and innovative learners with the desire to capitalize from the outstanding scientific community and cutting-edge resources uniquely available at Johns Hopkins University as well as from the progressive mindset of collaboration with industry – it is an incredibly nurturing environment for career growth that provides great opportunities for future employment.
VCA Lab website: http://hopkinsmedicine.org/vca-lab
We look for a fellow willing to tackle the challenges offered by the field of transplant immunology and immunoregulation. Under the guidance of Dr. Giorgio Raimondi (Associate Scientific Director of the VCA Lab), this section of the laboratory is devoted to pushing the boundaries of transplant and autoimmunity immunological research. Driven by the primary goal of devising effective strategies to promote immune tolerance, we focus on understanding novel mechanisms of T lymphocytes activation and regulation and the complex dynamics with their environment. Our projects are multidisciplinary. We work together with material scientists and protein engineers to devise innovative biomaterial-based drug delivery system to achieve fine-tuned immunomodulation when and where needed (including the use of lipid nanoparticles, brought to fame by current vaccine developments). In turn, these products become tools to study mechanisms of immunological tolerance. Similarly, we implement chimeric antigen receptor regulatory T cells (CAR-Treg) and study the molecular requirements for their effective implementation in the prevention of transplant rejection. Moreover, our unique micro-surgical expertise enables rapid progression from basic rodent models to translational large animal studies.
Our ideal candidate is a graduating student or junior postdoctoral fellow with the following characteristics:
· Has a strong background in immunology.
· Proficient in isolation of rodent cells and sterile tissue culture techniques of primary cells.
· Experienced in high parameter flow cytometry and other techniques like immunofluorescence microscopy, transcriptomic analysis, and basic molecular biology techniques.
· Excellent communicator, able to speak fluent English with great writing abilities.
Interested candidates should email: 1) a brief statement of how their research experience aligns to our focus, 2) their CV, and 3) the contact information of at least three references to: g.raimondi AT jhmi.edu
Tagged as: Life Sciences
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