PhD student in data-driven precision medicine Full-time NEW

PhD Student In Data-Driven Precision Medicine

The Department of Immunology, Genetics and Pathology at Uppsala University has a broad research profile with strong research groups focused on cancer, autoimmune and genetic diseases. A fundamental idea at the department is to stimulate translational research and thereby closer interactions between medical research and health care. Research is presently conducted in the following areas: medical and clinical genetics, clinical immunology, pathology, neuro biology, neuro-oncology, vascular biology, radiation science and molecular tools. Department activities are also integrated with the units for Oncology, Clinical Genetics, Clinical Immunology, Clinical Pathology, and Hospital Physics at Akademiska sjukhuset, Uppsala. The department has teaching assignments in several education programmes, including Master Programmes, at the Faculty of Medicine, and at the Disciplinary Domain of Science and Technology. The department has a yearly turnover of around SEK 500 million, out of which more than half is made up of external funding. The staff amounts to approximately 345 employees, out of which 100 are PhD-students, and there are in total more than 700 affiliated people.

Are you interested in working with data-driven precision medicine strategies for cancer treatment, with the support of competent and friendly colleagues in an international environment? Are you looking for an employer that invests in sustainable employeeship and offers safe, favourable working conditions? We welcome you to apply for a doctoral position at Uppsala University.

Duties This is a four-year pre-clinical doctoral position focused on the analysis and interpretation of high-throughput sequencing data to identify molecular drivers of cancer resistance and relapse, as well as to prioritize therapeutic targets for aggressive solid tumors.

The role involves working with both publicly available and internally generated datasets, with a particular focus on single-cell and bulk RNA sequencing. Responsibilities include independently performing data processing, analysis, and integration to drive assigned research projects. In addition, the position is expected to provide biostatistical support for other ongoing projects within the research group, including statistical analysis and data interpretation. The successful candidate is also expected to be highly motivated and willing to contribute to mentoring students at the undergraduate and master's levels.

This position requires close collaboration with the National Genomics Infrastructure, operating within SciLifeLab, and is fully on-site with no option for remote work.

Requirements To meet the entry requirements for doctoral studies, you must

– Already hold a Master's (second-cycle) degree in Molecular Medicine, Biology, Bioinformatics, or a related field, preferably with a focus on transcriptomics or cancer biology.

– Demonstrated expertise in bulk and single-cell RNA-seq data analysis, including data processing, integration, and interpretation.

– Experience in studying tumor heterogeneity and identifying biologically relevant subpopulations.

– Proficiency in data visualization and development of tools or databases for large-scale data exploration.

– Proficiency in English (written and spoken), with strong teamwork, communication, and mentoring skills.

About the employment The employment is a temporary position according to the Higher Education Ordinance chapter 5 § 7. Scope of employment 100 %. Starting date July 1, 2026 or as agreed. Placement: Rudbecklab, Uppsala.

For further information about the position, please contact: Xiaonan Zhang, Xiaonan.zhang@igp.uu.se or xiaonan.zhang@scilifelab.se.

Please submit your application by 8 May 2026, UFV-PA 2026/780.

Uppsala University is a broad research university with a strong international position. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all of our 7,600 employees and 53,000 students who, with curiosity and commitment, make Uppsala University one of Sweden's most exciting workplaces.