Postdoc in GPCR mechanosensing Full-time

Postdoctoral Position in GPCR Mechanosensation

We are looking for a highly motivated postdoc for a 1 year position to commence 1 October 2026 or as soon as possible thereafter.

The project is part of a larger cross institutional synergy project called 'GPCRmec: Quantitative investigation of GPCR mechanosensation' financed by the Novo Nordisk Foundation.

You will join the Mathiasen Group in the Department of Biomedical Sciences, in the theme of Molecular and Translational Pharmacology.

The Mathiasen group is one of multiple groups in the theme studying G protein-coupled receptors (GPCRs). We offer a dynamic and social work environment, where students at all levels (BSc, MSc, and PhD), postdocs, technicians and scientists from various cultures work together on a variety of interdisciplinary projects, and you will engage and collaborate with several colleagues in the group and theme.

The Department of Biomedical Sciences (BMI) is an interdisciplinary department with research groups focused on topics spanning from basic to translational science. Information on the department can be found at BMI.

The project aims to investigate the role of GPCR mechanosensation in GPCR pharmacology.

In the project will include the establishment of novel assays for the detection of the interplay between GPCR oligomerization and mechanosensation at the subcellular level, using a combination of fluorescence microscopy and live cell GPCR signalling assays.

The project will go deep to understand which mechanisms are at play when GPCR receptors respond to mechanical stress. A close collaboration with researchers from the Neils Bohr Institute and the Department of Chemistry will ensure access to the needed crossdisciplinarity expertise and microscopy equipment.

We are looking for a highly motivated and enthusiastic scientist, within the field(s) of Biophysics, Molecular or Cell Biology, Biochemistry, Life Sciences or alike, with the following competencies and experience:

• You have obtained PhD degree or equivalent
• You are experienced in confocal imaging and other types of fluorescence imaging
• You are experienced in investigating GPCR receptor signalling function and oligomerization
• You are experienced in working with mammalian cell culture
• You are experienced in working with standard molecular biology techniques
• You have good communication skills and ability to work in teams with e.g. MSc and PhD students
• You have excellent English skills both written and spoken

• Experience investigating the role of GPCRs in cardiovascular physiology, and in particular angiotensin II type I receptors will be an advance.
• Experience with image analysis procedures for quantitative microscopy
• Experience with assay-development for investigating GPCR oligomerization
• Experience with basic programming (MATLAB/Phyton)
• Experience using bioinformatics software e.g SnapGene or Geneious Prime

The place of employment is at the Department of Biomedical Sciences, Panum Institute, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and access to state-of-the-art equipment.

The average weekly working hours are 37 hours per week.

The position is a fixed-term position limited to a period of 1 year. The starting date is October 1st 2026 or after agreement.

Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 39,700 DKK/approx. 5,300 EUR (April 2026 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 18.07 % to your pension fund.

Foreign and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the Job Structure for Academic Staff at Universities 2025.

For further information please contact Signe Mathiasen; Signe.Mathiasen @sund.ku.dk.

Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Your online application must be submitted in English by clicking 'Apply now' below. Furthermore, your application must include the following documents/attachments – all in PDF format:

1. Motivated letter of application (max. one page).
2. CV incl. education, work/research experience, language skills and other skills relevant for the position.
3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
4. List of publications.

Deadline for applications: 20 July 2026, 23.59pm CET.

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.